• Clinical significance of serum adipokines levels in lung cancer 

      Kerenidi, T.; Lada, M.; Tsaroucha, A.; Georgoulias, P.; Mystridou, P.; Gourgoulianis, K. I. (2013)
      Adipokines have a significant effect on metabolism, immunoinflammatory responses as well as on carcinogenesis; therefore, we aimed at evaluating their potential predictive and prognostic significance in lung cancer. Eighty ...
    • Computation as a Tool for Glycogen Phosphorylase Inhibitor Design 

      Hayes, J. M.; Leonidas, D. D. (2010)
      Glycogen phosphorylase is an important therapeutic target for the potential treatment of type 2 diabetes. The importance of computation in the search for potent, selective and drug-like glycogen phosphorylase inhibitors ...
    • Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation 

      Parmenopoulou, V.; Chatzileontiadou, D. S. M.; Manta, S.; Bougiatioti, S.; Maragozidis, P.; Gkaragkouni, D. N.; Kaffesaki, E.; Kantsadi, A. L.; Skamnaki, V. T.; Zographos, S. E.; Zounpoulakis, P.; Balatsos, N. A. A.; Komiotis, D.; Leonidas, D. D. (2012)
      Five ribofuranosyl pyrimidine nucleosides and their corresponding 1,2,3-triazole derivatives have been synthesized and characterized. Their inhibitory action to Ribonuclease A has been studied by biochemical analysis and ...