Parcourir par sujet "NLR Family, Pyrin Domain-Containing 3 Protein"

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Leptin-depended NLRP3 inflammasome activation in osteoarthritic chondrocytes is mediated by ROS

Mourmoura E., Papathanasiou I., Trachana V., Konteles V., Tsoumpou A., Goutas A., Papageorgiou A.-A., Stefanou N., Tsezou A. (2022)

Leptin and ROS are implicated in the regulation of inflammatory pathways including NLRP3-inflammasome. We investigated the functional link between leptin, ROS and NLRP3-inflammasome formation/activation in osteoarthritis ...
The role of the NLRP3 inflammasome and the activation of IL-1β in the pathogenesis of chronic viral hepatic inflammation

Molyvdas A., Georgopoulou U., Lazaridis N., Hytiroglou P., Dimitriadis A., Foka P., Vassiliadis T., Loli G., Phillipidis A., Zebekakis P., Germenis A.E., Speletas M., Germanidis G. (2018)

Background and aims: Chronic viral hepatitis is a prevalent disease with major health implications. Its underlying pathophysiological mechanisms are not fully understood. IL-1β and the NLRP3 inflammasome involvement has ...