Sfoglia per Soggetto "MICROSATELLITE INSTABILITY"

Items 1-2 di 2

Mismatch repair hMSH2, hMLH1, hMSH6 and hPMS2 mRNA expression profiles in precancerous and cancerous urothelium

Vageli, D. P.; Giannopoulos, S.; Doukas, S. G.; Kalaitzis, C.; Giannakopoulos, S.; Giatromanolaki, A.; Koukoulis, G. K.; Touloupidis, S. (2013)

Changes in the expression of the mismatch repair (MMR) genes hMSH2, hMLH1, hMSH6 and hPMS2 reflect dysfunction of the DNA repair system that may allow the malignant transformation of tissue cells. The aim of the present ...
Phenotypic mismatch repair hMSH2 and hMLH1 gene expression profiles in primary non-small cell lung carcinomas

Vageli, D.; Daniil, Z.; Dahabreh, J.; Karagianni, E.; Vamvakopoulou, D. N.; Ioannou, M. G.; Scarpinato, K.; Vamvakopoulos, N. C.; Gourgoulianis, K. I.; Koukoulis, G. K. (2009)

Background: Defects in the human DNA mismatch repair genes (MMR) hMSH2 and hMLH1 arc responsible for the development of sporadic and hereditary colorectal cancers. The role of MMR genes in the pathogenesis of lung cancer ...