Sfoglia per Soggetto "LONG-TERM POTENTIATION"
Items 1-13 di 13
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The 5-HT1A receptor and recognition memory possible modulation of its behavioral effects by the nitrergic system
(2005)Functional activation of the 5-HT1A receptor inhibits cognition, although discrepant findings have also been reported. The present study was designed to investigate the role of the 5-HT1A receptor on recognition memory in ... -
Differential expression of NMDA and AMPA receptor subunits in rat dorsal and ventral hippocampus
(2006)Several studies have demonstrated anatomical and functional segregation along the dorsoventral axis of the hippocampus. This study examined the possible differences in the AMPA and NMDA receptor subunit composition and ... -
The Effect of Crocus sativus L. and Its Constituents on Memory: Basic Studies and Clinical Applications
(2015)Memory-related disorders are a common public health issue. Memory impairment is frequent in degenerative diseases (such as Alzheimer's disease and Parkinson disease), cerebral injuries, and schizophrenia. The dried stigma ... -
Effects of the nitric oxide synthase inhibitor L-NAME on different memory components as assessed in the object recognition task in the rat
(2010)Nitric oxide (NO) is sought to be an intracellular messenger in the central nervous system and its implication in learning and memory is well documented. Compounds that inhibit nitric oxide synthase (NOS), the key synthesizing ... -
Effects of the Nitric Oxide Synthase Inhibitor L-NAME on Recognition and Spatial Memory Deficits Produced by Different NMDA Receptor Antagonists in the Rat
(2010)There is consistent experimental evidence that noncompetitive antagonists of the N-methyl-D-aspartate (NMDA) receptor, such as ketamine, MK-801, and phencyclidine (PCP), impair cognition and produce psychotomimetic effects ... -
Fentanyl treatment reduces GABAergic inhibition in the CA1 area of the hippocampus 24 h after acute exposure to the drug
(2008)The effect of in vivo fentanyl treatment on synaptic transmission was studied in the CA1 area of the rat hippocampus. Animals were treated either with saline or fentanyl (4 x 80 mu g/kg, s.c./15 min). Intracellular in vitro ... -
The GABA(B) receptor and recognition memory: Possible modulation if its behavioral effects by the nitrergic system
(2003)Functional activation of the GABA(B) receptor inhibits learning and memory processes, though discrepant findings, in this context, have also been reported. The present study was designed to investigate the role of the ... -
Memantine and recognition memory: Possible facilitation of its behavioral effects by the nitric oxide (NO) donor molsidomine
(2007)The effects of the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist memantine on recognition memory were investigated in the rat by using the object recognition task. In addition, a possible interaction ... -
The nitric oxide donor molsidomine antagonizes age-related memory deficits in the rat
(2005)The effects of the nitric oxide (NO) donor molsidomine on aged rats' cognition were evaluated in two different behavioral tasks: the step-through passive avoidance paradigm and the object recognition test. Post-training ... -
Nitric oxide donor molsidomine attenuates psychotomimetic effects of the NMDA receptor antagonist MK-801
(2006)There is experimental evidence indicating that the noncompetitive NMDA receptor antagonist MK-801 impairs cognition and produces a series of schizophrenia-like symptoms in rodents (hypermotility, stereotypies, and ataxia). ... -
PKC-epsilon activation is required for recognition memory in the rat
(2013)Activation of PKC epsilon, an abundant and developmentally regulated PKC isoform in the brain, has been implicated in memory throughout life and across species. Yet, direct evidence for a mechanistic role for PKC epsilon ... -
The role of nitric oxide in the object recognition memory
(2015)The novel object recognition task (NORT) assesses recognition memory in animals. It is a non-rewarded paradigm that it is based on spontaneous exploratory behavior in rodents. This procedure is widely used for testing the ... -
Synaptic Plasticity: A Unifying Model to Address Some Persisting Questions
(2011)Since it was first observed, synaptic plasticity has been considered as the experimental paradigm most likely to provide us with an understanding of how information is stored in the vertebrate brain. Various types have ...