Auflistung Nach Schlagwort "DIVALENT METAL-IONS"
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Inhibition of human poly(A)-specific ribonuclease (PARN) by purine nucleotides: kinetic analysis
(2009)Poly(A)-specific ribonuclease (PARN) is a cap-interacting and poly(A)-specific 3'-exoribonuclease that efficiently degrades mRNA poly(A) tails. Based on the enzyme's preference for its natural substrates, we examined the ... -
Modulation of Poly(A)-specific Ribonuclease (PARN): Current Knowledge and Perspectives
(2012)Deadenylation is the exoribonucleolytic shortening of eukaryotic poly(A) tails. It is often the first and rate-limiting step for mRNA decay and translational silencing. The process is catalysed by a diversity of deadenylases, ...