• In vitro activity of dietary flavonol congeners against human cancer cell lines 

      Tsimplouli, C.; Demetzos, C.; Hadzopoulou-Cladaras, M.; Pantazis, P.; Dimas, K. (2012)
      Flavonoids have physiological activity and a variety of pharmacological properties, including anticancer activity in vitro, but structure-anticancer activity relationships are unclear. The objectives of this work were to ...
    • Quercetin accumulates in nuclear structures and triggers specific gene expression in epithelial cells 

      Notas, G.; Nifli, A. P.; Kampa, M.; Pelekanou, V.; Alexaki, V. I.; Theodoropoulos, P.; Vercauteren, J.; Castanas, E. (2012)
      Quercetin is a flavonol modifying a number of cell processes in different cell lines. Here, we present evidence that nonconjugated quercetin enters cells possibly via organic anion transporter polypeptides and quickly ...
    • The ubiquitin-proteasome system in glioma cell cycle control 

      Vlachostergios, P. J.; Voutsadakis, I. A.; Papandreou, C. N. (2012)
      A major determinant of cell fate is regulation of cell cycle. Tight regulation of this process is lost during the course of development and progression of various tumors. The ubiquitin-proteasome system (UPS) constitutes ...