Πλοήγηση ανά Θέμα "Caenorhabditis elegans"
Αποτελέσματα 1-5 από 5
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DIANA-mirExTra v2.0: Uncovering microRNAs and transcription factors with crucial roles in NGS expression data
(2016)Differential expression analysis (DEA) is one of the main instruments utilized for revealing molecular mechanisms in pathological and physiological conditions. DIANA-mirExTra v2.0 (http://www.microrna. gr/mirextrav2) ... -
Healthspan improvement and anti-aggregation effects induced by a marine-derived structural proteasome activator
(2022)Proteasome activation has been shown to promote cellular and organismal healthspan and to protect against aggregation-related conditions, such as Alzheimer's disease (AD). Various natural compounds have been described for ... -
Mechanisms of engineered nanoparticle induced neurotoxicity in Caenorhabditis elegans
(2019)The wide-spread implementation of nanoparticles poses a major health concern. Unique biokinetics allow them to transfer to neurons throughout the body and inflict neurotoxicity, which is challenging to evaluate solely in ... -
Network analysis in aged C. elegans reveals candidate regulatory genes of ageing
(2021)Ageing is a biological process guided by genetic and environmental factors that ultimately lead to adverse outcomes for organismal lifespan and healthspan. Determination of molecular pathways that are affected with age and ... -
We are what we eat: Ubiquitin–proteasome system (UPS) modulation through dietary products
(2020)During lifetime, the molecular mechanisms that are responsible for cellular defense against adverse conditions such as oxidative and heat stress tend to be less efficient, thus gradually leading to the natural phenomenon ...