Πλοήγηση ανά Θέμα "COLORECTAL-CANCER"
Αποτελέσματα 1-16 από 16
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Association of VEGF-A Splice Variant mRNA Expression With Outcome in Bevacizumab-Treated Patients With Metastatic Breast Cancer
(2014)We studied tissue mRNA levels of VEGF-Axxxa angiogenic versus VEGF-Axxxb anti-angiogenic isoforms by means of specially designed PCR assays in two parallel cohorts of metastatic breast cancer patients, one treated with ... -
Breast cancer risk in relation to most prevalent IgE specific antibodies: A case control study in Greece
(2007)Background: This study aims to explore the debatable role of allergy in breast cancer (BC) by using country-specific biological markers, namely levels of the most prevalent allergen -specific immunoglobulin E in Greece. ... -
Calprotectin, Calgranulin C, and Other Members of the S100 Protein Family in Inflammatory Bowel Disease
(2011)Background Since their discovery, S100 proteins have been associated with diverse diseases of inflammatory, degenerative, or malignant nature. Due to their participation in inflammation, they have also been studied with ... -
Chromogenic in situ Hybridization Analysis of EGFR Gene Copies in Colon Adenocarcinoma Based on Intra-Operative Imprints and Tissue Microarrays
(2009)Background: Although Epidermal Growth Factor Receptor (EGFR) over expression is a frequent event in colon adenocarcinoma (CA), identification of EGFR gene deregulation mechanisms - combined to k-ras mutations - remains the ... -
Curcumin analogues as possible anti-proliferative & anti-inflammatory agents
(2011)A series of novel curcumin analogues has been designed, synthesized and tested in vitro/in vivo as potential multi-target agents. Their anti-proliferative and anti-inflammatory activities were studied. Compounds 1b and 2b ... -
Cytolytic T-cell response against Epstein-Barr virus in lung cancer patients and healthy subjects
(2010)Background: This study aimed to examine whether EBV seropositive patients with lung cancer have an altered virus-specific CTL response, as compared to age-matched healthy controls and whether any variation in this response ... -
Detection of microsatellite instability in sporadic cardiac myxomas
(1999)Objective: Microsatellite instability (MIN) is an early event in DNA repair-deficient associated diseases and reflects an elevated mutation rate in the genome of neoplastic cells. Sporadic cardiac myxomas are the most ... -
FDG-PET for detecting local tumor recurrence of ablated liver metastases: a diagnostic meta-analysis
(2012)Context: Scanty reports have focused on FDG-PET after radiofrequency ablation (RFA), for recurrence of hepatic metastases. Objective: To assess FDG-PET diagnostic accuracy on detection of recurrent hepatic lesions. Methods: ... -
The Glasgow Prognostic Score (GPS) predicts toxicity and efficacy in platinum-based treated patients with metastatic lung cancer
(2012)Purpose: Lung cancer is the most common cause of cancer death. A cumulative prognostic score based on C-reactive protein and albumin, termed the Glasgow Prognostic Score (GPS), indicates the presence of systemic inflammatory ... -
High-Resolution Melting approaches towards plant fungal molecular diagnostics
(2015)Reliable and early molecular detection of phytopathogenic fungi is crucial in an era where the expansion of global trade in plant material is undoubtedly increasing the risk of invasive outbreaks, with devastating effects ... -
Immunophenotypic Evaluation of DNA Mismatch Repair Markers in 2 Cases of Synchronous Histomorphologically Distinct Gastric Adenocarcinomas With Gastrointestinal Stromal Tumors of the Proximal Small Bowel
(2010)Objectives: To assess the prognostic value of combined mismatch DNA repair (MMR) phenotyping in 2 synchronous histomorphologically distinct gastric adenocarcinomas (GADCs), each accompanied by gastrointestinal stromal ... -
Potential Role of the Alcohol and Smoking in the Squamous Cell Carcinoma of the Head And Neck: Review of the Current Literature and New Perspectives
(2011)Alcohol and tobacco are responsible for a very large proportion of chronic disease and some tumors in particular may be the result of interactions between the two risk factors. The present systematic literature review was ... -
The role of MTHFR gene in multiple myeloma
(2008)Case-control studies investigating associations between multiple myeloma (MM) and the C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) have provided controversial results. In an attempt to ... -
Study of the interaction among Notch pathway receptors, correlation with stemness, as well as their interaction with CD44, dipeptidyl peptidase-IV, hepatocyte growth factor receptor and the SETMAR transferase, in colon cancer stem cells
(2013)Context: The Notch signaling pathway is one of the most important pathways during normal development and implicated in self-renewal of adult stem cells and differentiation of progenitor cells. Abnormal expression of Notch ... -
Use of Fibrates and Cancer Risk: A Systematic Review and Meta-Analysis of 17 Long-Term Randomized Placebo-Controlled Trials
(2012)Background: Fibrates comprise a class of well-established antilipidemic agents that significantly reduce cardiovascular events. Given the concerns of cancer with fibrate therapy, we undertook a systematic review and ... -
Validated analysis of HIF-1 alpha expression in cancer cells using a controlled and comparative immunoassay
(2010)The immunoreactivity of hypoxia inducible factor 1 alpha (HIF-1 alpha) has been considered a reliable indicator of the HIF-1 pathway activation in tissue hypoxia. However, HIF-1 alpha immunoreactivity has been evaluated ...