Sfoglia per Autore "Voorde, J. V."
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Synthesis and biological evaluation of unsaturated keto and exomethylene D-arabinopyranonucleoside analogs: Novel 5-fluorouracil analogs that target thymidylate synthase
Tzioumaki, N.; Manta, S.; Tsoukala, E.; Voorde, J. V.; Liekens, S.; Komiotis, D.; Balzarini, J. (2011)The synthesis of pyrimidine unsaturated keto and exomethylene arabinopyranonucleoside analogs as potential antitumor and antiviral agents is described. Commercially available 1,2,3,4-tetra-O-acetyl-D-arabinopyranose (1) ...