Πλοήγηση ανά Συγγραφέα "Satra, M."
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Association of KLOTHO Gene Polymorphisms with Knee Osteoarthritis in Greek Population
Tsezou, A.; Furuichi, T.; Satra, M.; Makrythanasis, P.; Ikegawa, S.; Malizos, K. N. (2008)Based on the fact that klotho-deficient mice exhibit multiple aging phenotypes, including osteopenia and subchondral sclerosis of joints and on the recent observation that KLOTHO gene plays an important role in calcium/phosphate ... -
Correlation between radiation-induced telomerase activity and human telomerase reverse transcriptase mRNA expression in HeLa cells
Satra, M.; Tsougos, I.; Papanikolaou, V.; Theodorou, K.; Kappas, C.; Tsezou, A. (2006)Purpose: To quantify and correlate human telomerase reverse transcriptase (hTERT) mRNA expression with telomerase activity (TA) after ionizing irradiation of HeLa cells. Materials and methods: TA and hTERT mRNA expression ... -
Epigenetic regulation of hTERT promoter in hepatocellular carcinomas
Iliopoulos, D.; Satra, M.; Drakaki, A.; Poultsides, G. A.; Tsezou, A. (2009)Although hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide, the molecular pathogenesis of the disease has not been elucidated. Several studies have shown that telomerase activity and hTERT expression ... -
Follicular Fluid Oocyte/Cumulus-Free DNA Concentrations as a Potential Biomolecular Marker of Embryo Quality and IVF Outcome
Dimopoulou, M.; Anifandis, G.; Messini, C. I.; Dafopoulos, K.; Kouris, S.; Sotiriou, S.; Satra, M.; Vamvakopoulos, N.; Messinis, I. E. (2014)The present prospective study examined the follicular fluid oocyte/cumulus-free DNA concentrations (ff o/c-free DNA) during ovarian stimulation and the possible association between ff o/c-free DNA and embryological results ... -
The growth differentiation factor 5 (GDF5) core promoter polymorphism is not associated with knee osteoarthritis in the Greek population
Tsezou, A.; Satra, M.; Oikonomou, P.; Bargiotas, K.; Malizos, K. N. (2008)Genetic factors have been shown to play an important role in the etiology of osteoarthritis (OA). A functional single nucleotide polymorphism (SNP) +104T/C; rs143383 in the 5' UTR of the GDF5 gene was recently associated ... -
Impact of FXIIIA1, FII, FV, FGB and PAI1 Polymorphisms on Myocardial Perfusion: Correlation with Myocardial Single Photon Emission Computed Tomographic Imaging
Satra, M.; Samara, M.; Wozniak, G.; Kontos, A.; Valotassiou, V.; Tsougos, I.; Kollia, P.; Georgoulias, P. (2010) -
Impact of TLR-4 Polymorphisms on Circulating Levels of Antibodies Against Helicobacter pylori
Manolakis, A. C.; Kapsoritakis, A. N.; Tiaka, E. K.; Satra, M.; Gerovassili, A.; Tsiompanidis, I.; Vamvakopoulos, N.; Potamianos, S. P. (2010) -
Influence of Interleukin 1 alpha (IL-1 alpha), IL-4, and IL-6 Polymorphisms on Genetic Susceptibility to Chronic Osteomyelitis
Tsezou, A.; Poultsides, L.; Kostopoulou, F.; Zintzaras, E.; Satra, M.; Kitsiou-Tzeli, S.; Malizos, K. N. (2008)The association between cytokine gene polymorphisms and chronic osteomyelitis was investigated in order to determine whether genetic variability in cytokine genes predisposes to osteomyelitis susceptibility. Significant ... -
Leptin receptor isoforms mRNA expression in peripheral blood mononuclear cells from patients with chronic viral hepatitis
Stefanou, N.; Satra, M.; Papanikolaou, V.; Kalala, F.; Gatselis, N.; Germenis, A.; Dalekos, G. N.; Tsezou, A. (2006)There is accumulating evidence that leptin has a pleiotropic role in hematopoiesis, immune response, fibrogenesis, and hepatocarcinogenesis. We investigated the expression of leptin and leptin receptor (OB-R) at the protein ... -
On the mechanism of phenotypic conversion of human cervical adenocarcinoma HeLa cells surviving infection by influenza B virus: Potential implications for biological management of adenocarcinomas
Sioutopoulou, D. O.; Plakokefalos, E.; Arvanitis, L.; Athanassiou, E.; Venizelos, J.; Kaplanis, K.; Destouni, C.; Nomikos, I.; Satra, M.; Vamvakopoulos, N. C. (2008)We infected HeLa cells with low (10(-9) units), medium (10(-6) units), and high (10(-2) units) influenza B titers and compared the resulting human papilloma virus (HPV), retinoic acid receptor a subunit (RAR alpha) and ... -
Real-time quantification of human telomerase reverse transcriptase mRNA in liver tissues from patients with hepatocellular cancer and chronic viral hepatitis
Satra, M.; Gatselis, N.; Iliopoulos, D.; Zacharoulis, D.; Dalekos, G. N.; Tsezou, A. (2007)We determined, for the first time, the human telomerase reverse transcriptase (hTERT) mRNA expression, using real-time quantitative PCR, in liver tissues from patients with hepatocellular cancer (HCC; n = 13), chronic ... -
Residual telomerase activity as a marker of cell survival after exposure to ionizing radiation in vitro
Tsezou, A.; Satra, M.; Tsougos, Y.; Theodorou, K.; Papanikolaou, V.; Mavroidis, P.; Vamvakopoulos, N.; Kappas, C. (2004) -
Role of Hyperglycemia in Isogeneic Islet Transplantation: An Experimental Animal Study
Nomikos, I.; Kalogerakos, K.; Athanasiou, E.; Plakokefales, E.; Sioutopoulou, D.; Satra, M.; Vamvakopoulos, N. C. (2008)Objective: Study the role of hyperglycemia-induced beta cell loss on grafted islet destruction. Design: Male inbred rats were made diabetic by streptozotocin administration and used as islet donors and/or isograft recipients ... -
Sequence variations in the FII, FV, F13A1, FGB and PAI-1 genes are associated with differences in myocardial perfusion
Satra, M.; Samara, M.; Wosniak, G.; Tzavara, C.; Kontos, A.; Valotassiou, V.; Vamvakopoulos, N. K.; Tsougos, I.; Aleporou-Marinou, V.; Patrinos, G. P.; Kollia, P.; Georgoulias, P. (2011)Aims: Coronary artery disease (CAD) is a significant cause of morbidity and mortality in modern societies. The association between genetic markers and CAD is still poorly understood. In this study, we evaluated the effect ... -
Sequence-based genotyping HPV L1 DNA and RNA transcripts in clinical specimens
Satra, M.; Vamvakopoulou, D. N.; Sioutopoulou, D. O.; Kollia, P.; Kiritsaka, A.; Sotiriou, S.; Antonakopoulos, G.; Alexandris, E.; Costantoulakis, P.; Vamvakopoulos, N. C. (2009)We developed a direct sequence-based genotyping method to detect single and multiple HPV L1 DNA and RNA types in genital and dermatological specimens. Our method couples PCR amplification of a highly conserved HPV L1 segment ... -
Telomerase reverse transcriptase mRNA expression in peripheral lymphocytes of patients with chronic HBV and HCV infections
Satra, M.; Dalekos, G. N.; Kollia, P.; Vamvakopoulos, N.; Tsezou, A. (2005)Telomerase activity is present at low levels in peripheral lymphocytes (PL) and is upregulated upon activation, possibly protecting PL from telomere shortening. As decreased telomere length is considered a sign of cellular ... -
TLR4 gene polymorphisms: evidence for protection against type 2 diabetes but not for diabetes-associated ischaemic heart disease
Manolakis, A. C.; Kapsoritakis, A. N.; Tiaka, E. K.; Sidiropoulos, A.; Gerovassili, A.; Satra, M.; Vamvakopoulou, D.; Tsiopoulos, F.; Papanas, N.; Skoularigis, I.; Potamianos, S. P.; Vamvakopoulos, N. (2011)Objective: Several factors either predisposing or protecting from the onset of diabetes mellitus type 2 (DM2) have been proposed. Two specific polymorphisms of toll-like receptor 4 (TLR4; Asp299Gly and Thr399Ile) have ...