Browsing by Author "Pavlopoulou, A."
Now showing items 1-3 of 3
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A Comprehensive Phylogenetic Analysis of Deadenylases
Pavlopoulou, A.; Vlachakis, D.; Balatsos, N. A. A.; Kossida, S. (2013)Deadenylases catalyze the shortening of the poly(A) tail at the messenger ribonucleic acid (mRNA) 3'-end in eukaryotes. Therefore, these enzymes influence mRNA decay, and constitute a major emerging group of promising ... -
Emerging molecular networks common in ionizing radiation, immune and inflammatory responses by employing bioinformatics approaches
Georgakilas, A. G.; Pavlopoulou, A.; Louka, M.; Nikitaki, Z.; Vorgias, C. E.; Bagos, P. G.; Michalopoulos, I. (2015)Efficient radiation therapy is characterized by enhanced tumor cell killing involving the activation of the immune system (tumor immunogenicity) but at the same time minimizing chronic inflammation and radiation adverse ... -
An Integrated In Silico Approach to Design Specific Inhibitors Targeting Human Poly(A)-Specific Ribonuclease
Vlachakis, D.; Pavlopoulou, A.; Tsiliki, G.; Komiotis, D.; Stathopoulos, C.; Balatsos, N. A. A.; Kossida, S. (2012)Poly(A)-specific ribonuclease (PARN) is an exoribonuclease/deadenylase that degrades 3'-end poly(A) tails in almost all eukaryotic organisms. Much of the biochemical and structural information on PARN comes from the human ...