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Browsing by Author "Panotopoulou, E."

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    • Identification of novel E6-E7 sequence variants of human papillomavirus 16 

      Tsakogiannis, D.; Kyriakopoulou, Z.; Amoutzias, G.; Ruether, I. G. A.; Dimitriou, T. G.; Panotopoulou, E.; Markoulatos, P. (2013)
      The rate of evolution of the human papillomavirus 16 (HPV16) genome is low. However, the ability of the E6 oncoprotein to interact with distinct p53 variants causes selective pressure on the E6 gene. In addition, intratypic ...

    • Prevalence of HPV16 E1-1374 boolean AND 63nt variants in Greek women 

      Tsakogiannis, D.; Kyriakopoulou, Z.; Darmis, F.; Ruether, I. G. A.; Dimitriou, T. G.; Orfanoudakis, G.; Panotopoulou, E.; Markoulatos, P. (2014)
      Recent studies have focused on sequence variation of the HPV16 E1 gene. The present study investigates the prevalence of E1-1374<^>63nt duplication in the Greek population, and the sequence variation at the 5 ' end of the ...

    • Sequence variation analysis of the E2 gene of human papilloma virus type 16 in cervical lesions from women in Greece 

      Tsakogiannis, D.; Ruether, I. G. A.; Kyriakopoulou, Z.; Pliaka, V.; Theoharopoulou, A.; Skordas, V.; Panotopoulou, E.; Nepka, C.; Markoulatos, P. (2012)
      The E2 gene of human papilloma virus is expressed at the early stage of the viral life cycle, encoding the E2 transcription factor, and regulates the expression of E6 and E7 oncogenes. Disruption of E2 gene due to viral ...