Browsing by Author "Lang, F."
Now showing items 1-2 of 2
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Steroidal Cardiac Na+/K (+) ATPase Inhibitors Exhibit Strong Anti-Cancer Potential in vitro and in Prostate and Lung Cancer Xenografts in vivo
Dimas, K.; Papadopoulou, N.; Baskakis, C.; Prousis, K. C.; Tsakos, M.; Alkahtani, S.; Honisch, S.; Lang, F.; Calogeropoulou, T.; Alevizopoulos, K.; Stournaras, C. (2014)Sodium potassium pump (Na+/K+ ATPase) is a validated pharmacological target for the treatment of congestive heart failure. Recent data with inotropic drugs such as digoxin & digitoxin (digitalis) suggest a potent anti-cancer ... -
A Steroidal Na+/K+ ATPase Inhibitor Triggers Pro-apoptotic Signaling and Induces Apoptosis in Prostate and Lung Tumor Cells
Honisch, S.; Alkahtani, S.; Kounenidakis, M.; Liu, G. L.; Alarifi, S.; Al-Yahya, H.; Dimas, K.; AlKahtane, A. A.; Prousis, K. C.; Al-Dahmash, B.; Calogeropoulou, T.; Alevizopoulos, K.; Lang, F.; Stournaras, C. (2014)Recently we have reported potent anti-cancer actions of various steroidal Na+/K+ ATPase inhibitors in multiple cell lines. Furthermore, the most powerful compound identified in this study, the 3-[(R)-3-pyrrolidinyl]oxime ...