Parcourir par auteur "Bovee, M. L."
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A unique hydrophobic cluster near the active site contributes to differences in borrelidin inhibition, among threonyl-tRNA synthetases
Ruan, B.; Bovee, M. L.; Sacher, M.; Stathopoulos, C.; Poralla, K.; Francklyn, C. S.; Söll, D. (2005)Borrelidin, a compound with anti-microbial and anti-angiogenic properties, is a known inhibitor of bacterial and eukaryal threonyl-tRNA synthetase (ThrRS). The inhibition mechanism of borrelidin is not well understood. ...