Πλοήγηση ανά Θέμα "meta-analysis"
Αποτελέσματα 41-57 από 57
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Methylenetetrahydrofolate reductase gene and susceptibility to breast cancer: a meta-analysis
(2006)The methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms have been linked to the risk of developing breast cancer. A meta-analysis of 18 case-control studies investigating the association between the C677T and ... -
Misoprostol prior to hysteroscopy in premenopausal and post-menopausal women. A systematic review and meta-analysis
(2012)Although several randomized controlled trials (RCTs) have examined the effect of misoprostol prior to hysteroscopy for cervical dilatation, no solid conclusion has been reached. We therefore set out to perform a meta-analysis ... -
MTHFR gene polymorphisms and response to chemotherapy in colorectal cancer: a meta-analysis
(2009)Aims: Pharmacogenetic studies investigating the relationship between MTHFR gene polymorphisms and response to fluorouracil-based chemotherapy in patients with colorectal cancer have produced inconclusive results. In an ... -
A Multipoint Method for Meta-Analysis of Genetic Association Studies
(2010)Meta-analyses of genetic association studies are usually performed using a single polymorphism at a time, even though in many cases the individual studies report results from partially overlapping sets of polymorphisms. ... -
A Network Meta-analysis of Randomized Controlled Trials of Induction Treatments in Acute Myeloid Leukemia in the Elderly
(2011)Background: The optimal induction treatment of acute myeloid leukemia (AML) in the clinically and biologically heterogeneous group of elderly patients is not well-defined since direct comparisons between treatments is ... -
Polymorphisms of the endothelial nitric oxide synthase gene in breast cancer: a genetic association study and meta-analysis
(2010)The endothelial nitric oxide synthase gene (NOS3) has been proposed as a candidate gene for breast cancer (BC), however, the specific role of variants and haplotypes has not been clarified. We examined the association of ... -
Polymorphisms of the insulin receptor and the insulin receptor substrates genes in polycystic ovary syndrome: A Mendelian randomization meta-analysis
(2010)Polycystic ovary syndrome (PCOS) is a heterogeneous condition with unknown aetiology which is considered to be the most common endocrine disorder in women of reproductive age. In this work we investigated the association ... -
Randomized Trials of Dopamine Agonists in Restless Legs Syndrome: A Systematic Review, Quality Assessment, and Meta-Analysis
(2010)Background: The use of dopamine agonists (DAs) for the treatment of restless legs syndrome (RLS) has been assessed in numerous randomized clinical trials (RCTs). Objectives: The aims of this study were to assess the reporting ... -
The relationship between C677T methylenetetrahydrofolate reductase gene polymorphism and retinopathy in type 2 diabetes: a meta-analysis
(2005)The association between retincipathy in type 2 diabetes [diabetic retinopathy (DR)] and the C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene has been investigated in several case-control studies. ... -
The role of G196A polymorphism in the brain-derived neurotrophic factor gene in the cause of Parkinson's disease: a meta-analysis
(2005)The association between Parkinson's disease (PD) and the G196A polymorphism in the brain-derived neurotrophic factor (BDNF) gene has been investigated in several case-control studies, producing contradictory results: one ... -
The role of MTHFR gene in multiple myeloma
(2008)Case-control studies investigating associations between multiple myeloma (MM) and the C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) have provided controversial results. In an attempt to ... -
Spatial and temporal distribution of p,p′-DDE (1‑dichloro‑2,2‑bis (p‑chlorophenyl) ethylene) blood levels across the globe. A systematic review and meta-analysis
(2019)Background: Although p,p′‑DDT (1,1,1‑trichloro-2,2‑bis (p‑chlorophenyl)‑ethane) has been banned for decades in most countries, its major metabolite p,p′-DDE (1‑dichloro‑2,2‑bis (p‑chlorophenyl) ethylene) is still detected ... -
Synopsis and Synthesis of Candidate-Gene Association Studies in Chronic Lymphocytic Leukemia: The CUMAGAS-CLL Information System
(2009)A comprehensive and systematic assessment of the current status of candidate-gene association studies for chronic lymphocytic leukemia (CLL) was conducted. Data from 989 candidate-gene association studies (1992-2009) ... -
Synthesis of genetic association studies for pertinent gene-disease associations requires appropriate methodological and statistical approaches
(2008)Objective: The aim of the study was to consider statistical and methodological issues affecting the results of meta-analysis of genetic association studies for pertinent gene-disease associations. Although the basic ... -
Trends in meta-analysis of genetic association studies
(2008)The number of published genetic association studies (GASs) is increasing tremendously due to the availability of mapped single-nucleotide polymorphisms (SNPs) and advances in genotyping technologies. A search in HuGENet ... -
Vaginal progesterone gel for luteal phase support in IVF/ICSI cycles: a meta-analysis
(2010)Objective: To investigate whether vaginal progesterone gel may result in similar or higher pregnancy rates compared with all other vaginal progesterone forms when used for luteal-phase support. Design: Meta-analysis of ... -
Variants of the Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Gene and Risk of Stroke: A HuGE Gene-Disease Association Review and Meta-Analysis
(2009)Variants of the arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene have been implicated as a risk factor for stroke. However, genetic association studies that have examined the association between ALOX5AP gene ...