Πλοήγηση ανά Θέμα "CELLS"

Increased oxidative stress in exudative pleural effusions - A new marker for the differentiation between exudates and transudates?

Papageorgiou, E.; Kostikas, K.; Kiropoulos, T.; Karetsi, E.; Mpatavanis, G.; Gourgoulianis, K. I. (2005)

Study objectives: Oxidative stress has been associated with various respiratory disorders. We tested the hypothesis that exudates would present higher levels of oxidative stress compared to transudates, expressing the ...

Increased serum levels of YKL-40 in patients with inflammatory bowel disease

Koutroubakis, I. E.; Petinaki, E.; Dimoulios, P.; Vardas, E.; Roussomoustakaki, M.; Maniatis, A. N.; Kouroumalis, E. A. (2003)

Background and aims: Initiation of a fibrotic process has been suggested as part of the intestinal response to chronic inflammation in inflammatory bowel disease. YKL-40 has been proposed as a new serum marker of fibrosis. ...

Indoleamine 2,3-dioxygenose (IDO) expression in lung cancer

Karanikas, V.; Zamanakou, M.; Kerenid, T.; Dahabreh, J.; Hevas, A.; Nakou, M.; Gourgoulianis, K. I.; Germenis, A. E. (2007)

Background: The expression of indoleamine 2,3-dioxygenase (IDO) by tumor cells has been considered as a major tumor immune escape mechanism. The aim of this study was to investigate the expression of IDO in lung cancer ...

Inhibition of indoleamine 2,3-dioxygenase in mixed lymphocyte reaction affects glucose influx and enzymes involved in aerobic glycolysis and glutaminolysis in alloreactive T-cells

Eleftheriadis, T.; Pissas, G.; Yiannaki, E.; Markala, D.; Arampatzis, S.; Antoniadi, G.; Liakopoulos, V.; Stefanidis, I. (2013)

Indoleamine 2,3-dioxygenase (IDO) suppresses adaptive immunity. T-cell proliferation and differentiation to effector cells require increased glucose consumption, aerobic glycolysis and glutaminolysis. The effect of IDO on ...

Insulin NO-dependent action on airways smooth muscles

Papayianni, M.; Gourgoulianis, K. I.; Molyvdas, P. A. (2001)

In order to find out how insulin acts on airway smooth muscle and which mechanisms could be involved, we studied the effect of insulin on contraction induced, first, by KCI and, second, by Acetylcholine (Ach), before and ...

Internal translation initiation stimulates expression of the ARF/core+1 open reading frame of HCV genotype 1b

Boumlic, A.; Vassilaki, N.; Dalagiorgou, G.; Kochlios, E.; Kakkanas, A.; Georgopoulou, U.; Markoulatos, P.; Orfanoudakis, G.; Mavromara, P. (2011)

The hepatitis C virus possesses an alternative open reading frame overlapping the Core gene, whose products are referred to as Core+1 or alternative reading frame (ARF) or F protein(s). Extensive studies on genotype HCV-1 ...

Intracellular action of magnesium in airways smooth muscle relaxation in rabbit

Gourgoulianis, K. I.; Chatziparasidis, G.; Chatziefthimiou, A.; Molyvdas, P. A. (1999)

This study was designed to examine whether magnesium has an intracellular action on airways smooth muscle contraction. Tracheal muscle strips were obtained from six male rabbits and perfused in a bathing chamber. The muscle ...

Latanoprost therapy reduces the levels of TGF beta 1 and gelatinases in the aqueous humour of patients with exfoliative glaucoma

Konstas, A. G. P.; Koliakos, G. G.; Karabatsas, C. H.; Liakos, P.; Schlotzer-Schrehardt, U.; Georgiadis, N.; Ritch, R. (2006)

The aim of the present study was to evaluate the effect of latanoprost monotherapy on the aqueous humour concentrations of TGF-beta 1, MMP-2, TIMP-2, MMP-9 and gelatinolytic activity in patients treated for exfoliative ...

Levels of serum cytokines and acute phase proteins in patients with essential and cancer-related thrombocytosis

Alexandrakis, M. G.; Passam, F. H.; Moschandrea, I. A.; Christophoridou, A. V.; Pappa, C. A.; Coulocheri, S. A.; Kyriakou, D. S. (2003)

Essential thrombocytosis (ET) is a myeloproliferative disorder resulting in an increased production of abnormal platelets. Reactive thrombocytosis (RT) is occasionally observed in clinical situations including chronic ...

Long-term respiratory follow-up of H1N1 infection

Zarogoulidis, P.; Kouliatsis, G.; Papanas, N.; Spyratos, D.; Constantinidis, T. C.; Kouroumichakis, I.; Steiropoulos, P.; Mabroudi, M.; Matthaios, D.; Kerenidi, T.; Courcoutsakis, N.; Zarogoulidis, K.; Maltezos, E. (2011)

Background: The first case of 2009 pandemic influenza A (H1N1) virus infection was documented in our Hospital on 10th August 2009. Metdods and findings: Real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) ...

Low-Density Lipoprotein Receptor-Related Protein 5 (LRP5) Expression in Human Osteoarthritic Chondrocytes

Papathanasiou, I.; Malizos, K. N.; Tsezou, A. (2010)

The aim of this study was to investigate the activation of the Wnt/beta-catenin pathway in osteoarthritis and the role of low-density lipoprotein receptor-related protein 5 (LRP5) in human osteoarthritic chondrocytes. The ...

Magnesium as a relaxing factor of airway smooth muscles

Gourgoulianis, K. I.; Chatziparasidis, G.; Chatziefthimiou, A.; Molyvdas, P. A. (2001)

in the search for effective treatment of a life-threatening asthma attack, intravenous magnesium infusion has been studied in asthmatic patients because of its potential effect to reverse bronchospasm and improve pulmonary ...

Metformin reduces the expression of corticotropin-releasing hormone and urocortin in the endometrium of healthy women

Dafopoulos, K.; Vrekoussis, T.; Chalvatzas, N.; Messini, C. I.; Kalantaridou, S. N.; Georgoulias, P.; Messinis, I. E.; Makrigiannakis, A. (2013)

Objective: To investigate the effect of metformin administration on the expression of endometrial corticotrophin-releasing hormone (CRH) and urocortin (UCN) in the midluteal phase of the cycle. Design: Experimental study, ...

Molecular analysis of transferrin receptor mRNA expression in acute myeloid leukaemia

Kollia, P.; Stavroyianni, N.; Stamatopoulos, K.; Zoi, K.; Viniou, N.; Mantzourani, M.; Noguchi, C. T.; Paterakis, G.; Abazis, D.; Pangalos, C.; Loukopoulos, D.; Yataganas, X. (2001)

Transferrin receptor (TfR, CD71) is an integral membrane glycoprotein that mediates cellular uptake of iron. In most tissues, TfR expression is correlated positively with proliferation and regulated at the post-transcriptional ...

Molecular Cloning, Carbohydrate Specificity and the Crystal Structure of Two Sclerotium rolfsii Lectin Variants

Peppa, V. I.; Venkat, H.; Kantsadi, A. L.; Inamdar, S. R.; Bhat, G. G.; Eligar, S.; Shivanand, A.; Chachadi, V. B.; Satisha, G. J.; Swamy, B. M.; Skamnaki, V. T.; Zographos, S. E.; Leonidas, D. D. (2015)

SRL is a cell wall associated developmental-stage specific lectin secreted by Sclerotium rolfsii, a soil-born pathogenic fungus. SRL displays specificity for TF antigen (Gal13GalNAc--Ser//Thr) expressed in all cancer types ...

Molecular evidence for transferrin receptor 2 expression in all FAB subtypes of acute myeloid leukemia

Kollia, P.; Samara, M.; Stamatopoulos, K.; Belessi, C.; Stavroyianni, N.; Tsompanakou, A.; Athanasiadou, A.; Vainvakopoulos, N.; Laoutaris, N.; Anagnostopoulos, A.; Fassas, A. (2003)

We examined transferrin receptor (TfR) 1 and TfR2 mRNA expression in 50 acute myeloid leukemia (AML) patients by RT-PCR, with primers specific for exons 15-17 (TfR1), 3-5 (TfR2-alpha) and 4-5 (TfR2-beta) of the corresponding ...

Nocturnal hypertension is associated with an exacerbation of the endothelial damage in preeclampsia

Bouchlariotou, S.; Liakopoulos, V.; Dovas, S.; Giannopoulou, M.; Kiropoulos, T.; Zarogiannis, S.; Gatselos, G.; Zachopoulos, T.; Kyriakou, D. S.; Kallitsaris, A.; Messinis, I.; Stefanidis, I. (2008)

Background: Non-dipping pattern of circadian blood pressure in preeclampsia is associated with an increased risk of cardiovascular disease. The pathogenetic mechanisms of this relationship are still unclear. We investigated ...

Non-genomic effect of testosterone on airway smooth muscle

Kouloumenta, V.; Hatziefthimiou, A.; Paraskeva, E.; Gourgoulianis, K.; Molyvdas, P. A. (2006)

Background and purpose: Recent studies on blood vessels have provided evidence that testosterone may exert direct effects on smooth muscle. However, an acute effect on airway reactivity has not been shown yet. The aim of ...

Nonlinear binding of sex steroids to albumin and sex hormone binding globulin

Zeginiadou, T.; Kolias, S.; Kouretas, D.; Antonoglou, O. (1997)

We have studied the binding of sex steroids to albumin and sex hormone binding globulin (SHBG) using gel filtration chromatography for the separation of the bound from the free fraction of the steroid. It was found that ...

Oxidative stress and myocardial dysfunction in young rabbits after short term anabolic steroids administration

Germanakis, I.; Tsarouhas, K.; Fragkiadaki, P.; Tsitsimpikou, C.; Goutzourelas, N.; Champsas, M. C.; Stagos, D.; Rentoukas, E.; Tsatsakis, A. M. (2013)

The present study focuses on the short term effects of repeated low level administration of turinabol and methanabol on cardiac function in young rabbits (4 months-old). The experimental scheme consisted of two oral ...