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Αποτελέσματα 2501-2520 από 49724
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CD8+ PD-1+ T-cells and PD-L1+ circulating tumor cells in chemotherapy-naïve non-small cell lung cancer: towards their clinical relevance?
(2019)Background: Since tumor cells may escape from immune surveillance through the programmed cell death 1 (PD-1)/programmed death ligand (PD-L)1 axis, this study was designed in order to evaluate whether there is a correlation ... -
CD8+T lymphocytes in bronchoalveolar lavage in idiopathic pulmonary fibrosis
(2007)Background. Recently it was shown that in Idiopathic Pulmonary Fibrosis (IPF) tissue infiltrating CD8+ T lymphocytes (TLs) are associated with breathlessness and physiological indices of disease severity, as well as that ... -
CD8+T-cell auto-reactivity is dependent on the expression of the immunoproteasome subunit LMP7 in exposed to lipopolysaccharide antigen presenting cells and epithelial target cells
(2013)Proteasome generates peptides for presentation to CD8+ T-cells by antigen presenting cells (APCs) and peripheral cells. Inflammation alters proteasome to immunoproteasome, producing a different pool of peptides. The effect ... -
CD90/Thy-1, a cancer-associated cell surface signaling molecule
(2019)CD90 is a membrane GPI-anchored protein with one Ig V-type superfamily domain that was initially described in mouse T cells. Besides the specific expression pattern and functions of CD90 that were described in normal tissues ... -
CDK-inhibitor olomoucine inhibits cell death after exposure of cell lines to cytosine-arabinoside
(1999)Signal transduction for apoptosis or programmed cell death, after DNA damage in mammalian cells, is believed to involve activation of cyclin-dependent kinases (CDKs), especially CDK-1 (cdc2) and CDK-2. We used CDK-inhibitor ... -
CDMA RoFSO Links with Nonzero Boresight Pointing Errors over M Turbulence Channels
(2018)Radio-on-Free-Space Optical systems constitute a very attractive option for interconnecting central base stations with remote antenna units. Nonetheless, the optical signal propagation through the atmosphere is tremendously ... -
CDNs Content Outsourcing via Generalized Communities
(2009)Content distribution networks (CDNs) balance costs and quality in services related to content delivery. Devising an efficient content outsourcing policy is crucial since, based on such policies, CDN providers can provide ... -
CDNsim: A Simulation Tool for Content Distribution Networks
(2010)Content distribution networks (CDNs) have gained considerable attention in the past few years. Hence there is need for developing frameworks for carrying out CDN simulations. In this article we present a modeling and ... -
CDR-MAC: A protocol for full exploitation of directional antennas in ad hoc wireless networks
(2008)In this paper, we propose a new Medium Access Control (MAC) protocol for full exploitation of directional antennas in wireless networks. The protocol introduces a circular directional transmission of the Request To Send ... -
Ceci n'est pas une masque
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Cecorectal (CRA) versus ileorectal (IRA) anastomosis after colectomy for slow transit constipation (STC): a meta-analysis
(2022)Introduction: We conducted this meta-analysis, to compare cecorectal (CRA) and ileorectal anastomosis (IRA), regarding perioperative safety and efficacy, in patients submitted to colectomy for refractory slow transit ... -
Ceftazidime-avibactam to treat life-threatening infections by carbapenem-resistant pathogens in critically ill mechanically ventilated patients
(2020)Data on the effectiveness of ceftazidime-avibactam (CAZ-AVI) in critically ill, mechanically ventilated patients are limited. The present retrospective observational cohort study, which was conducted in two general intensive ... -
Ceftazidime/avibactam in the era of carbapenemase-producing Klebsiella pneumoniae: Experience from a national registry study
(2021)Background: Infections caused by KPC-producing Klebsiella pneumoniae (Kp) are associated with high mortality. Therefore, new treatment options are urgently required. Objectives: To assess the outcomes and predictors of ... -
Celiac Trunk and Hepatic Arteries: Anatomical Variations of Liver Arterial Supply as Detected with Multidetector Computed Tomography in 1,520 Patients and its Clinical Importance
(2020)Hepatic arterial variations are relatively common, but usually overlooked by radiologists, leading to iatrogenic complications or prolonging interventional or surgical procedures. Michels in 1966 classified hepatic arterial ... -
Celiomesenteric trunk demonstrated by multi-detector computed tomography angiography: two cases of a rare vascular variation
(2013)We present two cases of patients with celiomesenteric trunk in whom the celiac trunk and the superior mesenteric artery arise off a common vessel from the ventral part of the aorta, which was demonstrated by multi-detector ... -
Cell and extracellular matrix interaction models in benign mesothelial and malignant pleural mesothelioma cells in 2D and 3D in-vitro
(2021)Malignant pleural mesothelioma (MPM) is an aggressive tumour that grows in the pleural cavity. MPM spheroids released in the pleural fluid can form new tumour foci. Cell–cell, cell–extracellular matrix (ECM) interactions ... -
Cell death patterns due to warm ischemia or reperfusion in renal tubular epithelial cells originating from human, mouse, or the native hibernator hamster
(2018)Ischemia–reperfusion injury contributes to the pathogenesis of many diseases, with acute kidney injury included. Hibernating mammals survive prolonged bouts of deep torpor with a dramatic drop in blood pressure, heart, and ... -
Cell death-inducing effect of novel palladium(II) and platinum(II) complexes on non-small cell lung cancer cells in vitro
(2011)Purpose Treatment for lung cancer is still far from satisfying rates. Therefore, there is a need for novel anticancer agents. For this purpose, novel platinum and palladium complexes {[Pd(sac)(terpy)](sac).4H(2)O (Complex ...