• Microbleeds and the Effect of Anticoagulation in Patients with Embolic Stroke of Undetermined Source: An Exploratory Analysis of the NAVIGATE ESUS Randomized Clinical Trial 

      Shoamanesh A., Hart R.G., Connolly S.J., Kasner S.E., Smith E.E., Martí-Fàbregas J., Liu Y.Y., Uchiyama S., Mikulik R., Veltkamp R., O'Donnell M.J., Ntaios G., Muir K.W., Field T.S., Santo G.C., Olavarria V., Mundl H., Lutsep H., Berkowitz S.D., Sharma M. (2021)
      Importance: The reported associations of cerebral microbleeds with recurrent stroke and intracerebral hemorrhage have raised concerns regarding antithrombotic treatment in patients with a history of stroke and microbleeds ...
    • Midterm experience of Scarf osteotomy as a new technique in a General Orthopaedic Department 

      Samaras D., Gougoulias N., Varitimidis S., Hantes M., Karachalios T., Malizos K., Dailiana Z. (2019)
      Scarf osteotomy has become popular as a versatile procedure that could correct most cases of hallux valgus. The purpose of this study is to report the experience with scarf osteotomy performed as a new technique by different ...
    • Mycophenolate for the treatment of autoimmune hepatitis: Prospective assessment of its efficacy and safety for induction and maintenance of remission in a large cohort of treatment-naïve patients 

      Zachou, K.; Gatselis, N.; Papadamou, G.; Rigopoulou, E. I.; Dalekos, G. N. (2011)
      Background & Aims: Standard therapy for autoimmune hepatitis (AIH) is corticosteroids with or without azathioprine. However, 20% of patients do not respond or are intolerant to conventional treatment. Therefore, we evaluated ...
    • Obesity as a Risk Factor for Venous Thromboembolism Recurrence: A Systematic Review 

      Ntinopoulou P., Ntinopoulou E., Papathanasiou I.V., Fradelos E.C., Kotsiou O., Roussas N., Raptis D.G., Gourgoulianis K.I., Malli F. (2022)
      Background and Objectives: Venous thromboembolism (VTE) encompasses Deep Venous Thrombosis (DVT) and Pulmonary Embolism (PE). The duration of anticoagulant therapy following a VTE event partly relies on the risk of recurrent ...
    • Prediction of Early Recurrent Thromboembolic Event and Major Bleeding in Patients with Acute Stroke and Atrial Fibrillation by a Risk Stratification Schema: The ALESSA Score Study 

      Paciaroni M., Agnelli G., Caso V., Tsivgoulis G., Furie K.L., Tadi P., Becattini C., Falocci N., Zedde M., Abdul-Rahim A.H., Lees K.R., Alberti A., Venti M., Acciarresi M., D'Amore C., Mosconi M.G., Cimini L.A., Procopio A., Bovi P., Carletti M., Rigatelli A., Cappellari M., Putaala J., Tomppo L., Tatlisumak T., Bandini F., Marcheselli S., Pezzini A., Poli L., Padovani A., Masotti L., Vannucchi V., Sohn S.-I., Lorenzini G., Tassi R., Guideri F., Acampa M., Martini G., Ntaios G., Karagkiozi E., Athanasakis G., Makaritsis K., Vadikolias K., Liantinioti C., Chondrogianni M., Mumoli N., Consoli D., Galati F., Sacco S., Carolei A., Tiseo C., Corea F., Ageno W., Bellesini M., Colombo G., Silvestrelli G., Ciccone A., Scoditti U., Denti L., Mancuso M., Maccarrone M., Orlandi G., Giannini N., Gialdini G., Tassinari T., De Lodovici M.L., Bono G., Rueckert C., Baldi A., D'Anna S., Toni D., Letteri F., Giuntini M., Lotti E.M., Flomin Y., Pieroni A., Kargiotis O., Karapanayiotides T., Monaco S., Baronello M.M., Csiba L., Szabó L., Chiti A., Giorli E., Del Sette M., Imberti D., Zabzuni D., Doronin B., Volodina V., Michel P., Vanacker P., Barlinn K., Pallesen L.-P., Kepplinger J., Bodechtel U., Gerber J., Deleu D., Melikyan G., Ibrahim F., Akhtar N., Gourbali V., Yaghi S. (2017)
      Background and Purposes - This study was designed to derive and validate a score to predict early ischemic events and major bleedings after an acute ischemic stroke in patients with atrial fibrillation. Methods - The ...
    • Predictive value of telomerase reverse transcriptase expression in patients with high risk superficial bladder cancer treated with adjuvant BCG immunotherapy 

      Zachos, I.; Konstantinopoulos, P. A.; Vandoros, G. P.; Karamouzis, M. V.; Papatsoris, A. G.; Podimatas, T.; Papachristodoulou, A.; Chrisofos, M.; Deliveliotis, C.; Papavassiliou, A. G. (2009)
      We conducted a prospective study to determine whether expression of telomerase reverse transcriptase (hTERT) is associated with recurrence-free-survival (RFS) or development of invasive disease in patients with high risk ...
    • Predictors of hepatitis B surface antigen loss, relapse and retreatment after discontinuation of effective oral antiviral therapy in noncirrhotic HBeAg-negative chronic hepatitis B 

      Papatheodoridi M., Hadziyannis E., Berby F., Zachou K., Testoni B., Rigopoulou E., Gatselis N.K., Lyberopoulou A., Vlachogiannakos I., Manolakopoulos S., Dalekos G.N., Zoulim F., Papatheodoridis G.V. (2020)
      Reliable predictors of outcomes after treatment discontinuation in HBeAg-negative chronic hepatitis B (CHB) patients have not been established. We investigated the role of hepatitis B surface antigen (HBsAg), interferon-inducible ...
    • Predictors of Need for Critical Care Support, Adverse Events, and Outcome after Stroke Thrombolysis 

      Papamichalis P., Karagiannis S., Dardiotis E., Chovas A., Papadopoulos D., Zafeiridis T., Babalis D., Paraforos G., Zisopoulou V., Skoura A.-L., Staikos I., Bouliaris K., Papamichalis M., Hadjigeorgiou G., Komnos A. (2018)
      Background: Results from trials and international registries exhibit heterogeneity regarding safety, efficacy, markers of prognosis, and markers of the need for critical care support after intravenous thrombolysis (IVT) ...
    • Predictors of Recurrent Ischemic Stroke in Patients with Embolic Strokes of Undetermined Source and Effects of Rivaroxaban Versus Aspirin According to Risk Status: The NAVIGATE ESUS Trial 

      Hart R.G., Veltkamp R.C., Sheridan P., Sharma M., Kasner S.E., Bangdiwala S.I., Ntaios G., Shoamanesh A., Ameriso S.F., Toni D., Czlonkowska A., Lindgren A., Hankey G.J., Perera K.S., Shuaib A., Coutts S.B., Gagliardi R.J., Berkowitz S.D., Mundl H., Peters G., Connolly S.J., NAVIGATE ESUS Investigators (2019)
      Background: Embolic stroke of undetermined source (ESUS) identifies patients with cryptogenic ischemic stroke presumed due to embolism from several unidentified sources. Among patients with recent ESUS, we sought to determine ...
    • Previous Bladder Cancer History in Patients with High-Risk, Non-muscle-invasive Bladder Cancer Correlates with Recurrence and Progression: Implications of Natural History 

      Mitrakas, L. P.; Zachos, I. V.; Tzortzis, V. P.; Gravas, S. A.; Rouka, E. C.; Dimitropoulos, K. I.; Vandoros, G. P.; Karatzas, A. D.; Melekos, M. D.; Papavassiliou, A. G. (2015)
      Purpose The purpose of this study was to assess the correlation of previous bladder cancer history with the recurrence and progression of patients with high-risk non-muscle-invasive bladder cancer treated with adjuvant ...
    • Primary extranodal non Hodgkin's lymphoma of the head and neck in adults: A clinicopathological comparison between tonsillar and non tonsillar lymphomas 

      Economopoulos, T.; Fountzilas, G.; Kostourou, A.; Daniilidis, J.; Pavlidis, N.; Andreopoulou, H.; Nicolaou, A.; Papageorgiou, E.; Mellou, S.; Dervenoulas, J.; Stathakis, N. (1998)
      Primary extranodal NHL of the head and neck (HN-NHL) accounts for 10-20% of all cases of NHL. Despite their frequency, the natural history and biological behaviour of these lymphomas is poorly understood. In this study we ...
    • Prolonged Cardiac Monitoring and Stroke Recurrence: A Meta-analysis 

      Tsivgoulis G., Triantafyllou S., Palaiodimou L., Grory B.M., Deftereos S., Köhrmann M., Dilaveris P., Ricci B., Tsioufis K., Cutting S., Magiorkinis G., Krogias C., Schellinger P.D., Dardiotis E., Rodriguez-Campello A., Cuadrado-Godia E., Aguiar De Sousa D., Sharma M., Gladstone D.J., Sanna T., Wachter R., Furie K.L., Alexandrov A.V., Yaghi S., Katsanos A.H. (2022)
      Background and ObjectivesProlonged poststroke cardiac rhythm monitoring (PCM) reveals a substantial proportion of patients with ischemic stroke (IS) with atrial fibrillation (AF) not detected by conventional rhythm monitoring ...
    • Prospective comparative study of different endovenous thermal ablation systems for treatment of great saphenous vein reflux 

      Karathanos C., Spanos K., Batzalexis K., Nana P., Kouvelos G., Rousas N., Giannoukas A.D. (2021)
      Objective: The aim of our study was to compare three different endovenous thermal ablation (EVTA) modalities in the treatment of great saphenous vein (GSV) incompetence. Methods: We performed a single-center, prospective, ...
    • Real-world data on Len/Dex combination at second-line therapy of multiple myeloma: treatment at biochemical relapse is a significant prognostic factor for progression-free survival 

      Katodritou E., Kyrtsonis M.-C., Delimpasi S., Kyriakou D., Symeonidis A., Spanoudakis E., Vasilopoulos G., Anagnostopoulos A., Kioumi A., Zikos P., Aktypi A., Briasoulis E., Megalakaki A., Repousis P., Adamopoulos I., Gogos D., Kotsopoulou M., Pappa V., Papadaki E., Fotiou D., Nikolaou E., Giannopoulou E., Hatzimichael E., Giannakoulas N., Douka V., Kokoviadou K., Timotheatou D., Terpos E. (2018)
      We evaluated progression-free survival (PFS) rate of patients treated with lenalidomide/dexamethasone (Len/Dex), the efficacy of the combination, and the prognostic significance of treatment at biochemical vs. clinical ...
    • Real-world experience of extracranial carotid artery interventions for atherosclerotic disease during a 10-year period 

      Spanos K., Karathanos C., Lachanas V.A., Drakou A., Stamoulis K., Koutsias S., Giannoukas A.D. (2018)
      BACKGROUND: The aim of this study was to assess the long-term outcome of carotid disease treatment with endarterectomy or stenting (CEAor CAS) in a real-world setting during a 10-year period. METHODS: Asingle center ...
    • Recurrence of superficial vein thrombosis in patients with varicose veins 

      Karathanos C., Spanos K., Saleptsis V., Tsezou A., Kyriakou D., Giannoukas A.D. (2016)
      Objective: To investigate which factors other than history of superficial vein thrombosis (SVT) are associated with recurrent spontaneous SVT episodes in patients with varicose veins (VVs). Materials and methods: Patients ...
    • Recurrent horizontal transfer identifies mitochondrial positive selection in a transmissible cancer 

      Strakova A., Nicholls T.J., Baez-Ortega A., Ní Leathlobhair M., Sampson A.T., Hughes K., Bolton I.A.G., Gori K., Wang J., Airikkala-Otter I., Allen J.L., Allum K.M., Arnold C.L., Bansse-Issa L., Bhutia T.N., Bisson J.L., Blank K., Briceño C., Castillo Domracheva A., Corrigan A.M., Cran H.R., Crawford J.T., Cutter S.M., Davis E., de Castro K.F., De Nardi A.B., de Vos A.P., Delgadillo Keenan L., Donelan E.M., Espinoza Huerta A.R., Faramade I.A., Fazil M., Fotopoulou E., Fruean S.N., Gallardo-Arrieta F., Glebova O., Gouletsou P.G., Häfelin Manrique R.F., Henriques J.J.G.P., Horta R.S., Ignatenko N., Kane Y., King C., Koenig D., Krupa A., Kruzeniski S.J., Lanza-Perea M., Lazyan M., Lopez Quintana A.M., Losfelt T., Marino G., Martínez Castañeda S., Martínez-López M.F., Masuruli B.M., Meyer M., Migneco E.J., Nakanwagi B., Neal K.B., Neunzig W., Nixon S.J., Ortega-Pacheco A., Pedraza-Ordoñez F., Peleteiro M.C., Polak K., Pye R.J., Ramirez-Ante J.C., Reece J.F., Rojas Gutierrez J., Sadia H., Schmeling S.K., Shamanova O., Sherlock A.G., Steenland-Smit A.E., Svitich A., Tapia Martínez L.J., Thoya Ngoka I., Torres C.G., Tudor E.M., van der Wel M.G., Vițălaru B.A., Vural S.A., Walkinton O., Wehrle-Martinez A.S., Widdowson S.A.E., Zvarich I., Chinnery P.F., Falkenberg M., Gustafsson C.M., Murchison E.P. (2020)
      Autonomous replication and segregation of mitochondrial DNA (mtDNA) creates the potential for evolutionary conflict driven by emergence of haplotypes under positive selection for ‘selfish’ traits, such as replicative ...
    • Recurrent Stroke with Rivaroxaban Compared with Aspirin According to Predictors of Atrial Fibrillation: Secondary Analysis of the NAVIGATE ESUS Randomized Clinical Trial 

      Healey J.S., Gladstone D.J., Swaminathan B., Eckstein J., Mundl H., Epstein A.E., Haeusler K.G., Mikulik R., Kasner S.E., Toni D., Arauz A., Ntaios G., Hankey G.J., Perera K., Pagola J., Shuaib A., Lutsep H., Yang X., Uchiyama S., Endres M., Coutts S.B., Karliński M., Czlonkowska A., Molina C.A., Santo G., Berkowitz S.D., Hart R.G., Connolly S.J. (2019)
      Importance: The NAVIGATE ESUS randomized clinical trial found that 15 mg of rivaroxaban per day does not reduce stroke compared with aspirin in patients with embolic stroke of undetermined source (ESUS); however, it ...
    • Renal function and risk stratification of patients with embolic stroke of undetermined source 

      Ntaios G., Lip G.Y.H., Lambrou D., Michel P., Perlepe K., Eskandari A., Nannoni S., Sirimarco G., Strambo D., Vemmos K., Koroboki E., Manios E., Vemmou A., Rodríguez-Campello A., Cuadrado-Godia E., Roquer J., Arnao V., Caso V., Paciaroni M., Diez-Tejedor E., Fuentes B., Pardo J.R., Arauz A., Ameriso S.F., Pertierra L., Gómez-Schneider M., Hawkes M.A., Bandini F., Cano B.C., Mohedano A.M.I., Pastor A.G., Gil-Núñez A., Putaala J., Tatlisumak T., Barboza M.A., Karagkiozi E., Makaritsis K., Papavasileiou V. (2018)
      Background and Purpose-We aimed to assess if renal function can aid in risk stratification for ischemic stroke or transient ischemic attack (TIA) recurrence and death in patients with embolic stroke of undetermined source ...