Πλοήγηση ανά Θέμα "INDUCTION"
Αποτελέσματα 1-20 από 23
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Additive enhancement of apoptosis by TRAIL and fenretinide in metastatic breast cancer cells in vitro
(2014)Successful management of metastatic breast cancer still needs better chemotherapeutic approaches. The combination of fenretinide (4-HPR), a synthetic retinoid inducing apoptosis by ROS generation, and TRAIL, a cell death ... -
Bax protein expression in colorectal cancer: Association with p53, bcl-2 and patterns of relapse
(2001)This study evaluated the frequency and the prognostic significance of bax, bcl-2 and p53 proteins in stage B and C adenocarcinomas of the colon and rectum. Paraffin-embedded specimens from 268 patients with colorectal ... -
Chemopreventive activity of very low dose dietary tannic acid administration in hepatoma bearing C3H male mice
(1999)Tannins are plant polyphenols comprising a heterogeneous group of compounds. Tannic acid is a common tannin found in tea, coffee, immature fruits, etc. and it has also been used as a food additive. An increasing body of ... -
Clinical and experimental evidence of bcl-2 involvement in the response to photodynamic therapy
(2001)Purpose: The role of apoptosis related proteins in the response of human malignancies to photodynamic therapy (PDT) is under investigation. The aim of the study was to examine the role of p53 and of bcl-2 protein expression ... -
Cobalt induces hypoxia-inducible factor-1 alpha expression in airway smooth muscle cells by a reactive oxygen species- and PI3K-dependent mechanism
(2004)Cobalt can mimic hypoxia and has been implicated as a cause of lung defects. However, the effect of cobalt on airway smooth muscle (ASM) cells has not been analyzed in detail. In this article, we use primary cultures of ... -
Determination of the proper time for mating after oestrous synchronisation during anoestrous or oestrous by measuring electrical resistance of cervical mucus in ewes
(2015)The purpose of the present study was to investigate whether the electrical resistance values of the cervical mucus and/or blood estradiol-17 beta and progesterone concentrations at mating, after oestrous synchronisation ... -
A Foamy Virus Vector System for Stable and Efficient RNAi Expression in Mammalian Cells
(2011)The promise of the RNA interference (RNAi) technology is equally dependent on the efficiency and stability of gene silencing. The aim of the present study was the development of foamy virus (FV) vectors for stable RNAi, ... -
Foxp3 expression in human cancer cells
(2008)Objective: Transcription factor forkhead box protein 3 (Foxp3) specifically characterizes the thymically derived naturally occurring regulatory T cells (Tregs). Limited evidence indicates that it is also expressed, albeit ... -
Growth hormone response to thyrotrophin releasing hormone in women with polycystic ovarian syndrome
(1999)Recent clinical studies have suggested that women with polycystic ovarian syndrome (PCOS) may have disturbances of growth hormone (GH) kinetics and the GH/insulin-like growth factor (IGF)-I system. The knowledge that in ... -
The Indoleamine 2,3-dioxygenase Inhibitor 1-methyl-tryptophan Suppresses Mitochondrial Function, Induces Aerobic Glycolysis and Decreases Interleukin-10 Production in Human Lymphocytes
(2012)Background: Indoleamine 2,3-dioxygenase (IDO) suppresses adaptive immunity. It is known that IDO induces T-cell differentiation to regulatory T-cells (Treg) through tryptophan depletion and/or kynurenine pathway products. ... -
Novel Sequence Variations in the CER1 Gene Are Strongly Associated with Low Bone Mineral Density and Risk of Osteoporotic Fracture in Postmenopausal Women
(2012)Osteoporosis is a common skeletal disease characterized by a combination of low bone mass and increased fragility. In this case-control study, we investigated the possible association of two novel candidate genes, CER1 and ... -
Perforin down-regulation and adhesion molecules activation in pulmonary sarcoidosis - An induced sputum and BAL study
(2006)Background. Sarcoidosis is drought to be a T-helper type 1 cytokine-mediated disorder. Sputum induction has been proposed as a useful noninvasive method mainly for the assessment of airway diseases. However, it is unknown ... -
Plasma Indoleamine 2,3-Dioxygenase and Arginase Type I May Contribute to Decreased Blood T-Cell Count in Hemodialysis Patients
(2012)Background: Acquired immunity is impaired in hemodialysis (HD) patients, and decreased T-cell number may contribute. Indoleamine 2,3-dioxygenase (IDO) and arginase type I (ARG) catabolize tryptophane and arginine, respectively, ... -
Plasminogen activator activity in the porcine oviduct during the oestrous cycle
(2005)The mammalian oviduct is a dynamic tissue, which lies under the influence of ovarian steroids and produces proteins that affect various stages of fertilization and post-fertilization events. In this study, expression of ... -
The progesterone positive feedback effect in women after ovariectomy
(2013)Various ovarian substances regulate the secretion of gonadotrophins during the menstrual cycle, but there are still several unclarified issues. The aim of this study was to investigate the positive feedback effect of ... -
Relationship between electrical resistance of cervical mucus and ovarian steroid concentration at the time of artificial insemination in ewes
(2014)The purpose of this study was to investigate whether fertile or non-fertile inseminations (AI) in synchronized ewes are correlated with the electrical resistance of cervical mucus (ERCM) and the ovarian steroid concentration. ... -
A study of zearalenone cytotoxicity on human peripheral blood mononuclear cells
(2006)The mycotoxin zearalenone (ZEA) is a common contaminant of all major cereal grains worldwide with estrogenic and anabolic activity. We investigated the in vitro cytopathic effects of ZEA on freshly isolated human peripheral ... -
Suppression of humoral immune response to hepatitis B surface antigen vaccine in BALB/c mice by 1-methyl-tryptophan co-administration
(2011)Background and the purpose of the study: Indoleamine 2,3-dioxygenase (IDO) suppresses adaptive immune response. The purpose of this study was to determine the effect of the IDO inhibitor namely 1-methyl-DL-tryptophan ... -
Synchronisation of lambing with low doses of dexamethasone in Chios ewes - Short communication
(2008)The purpose of the present study was to investigate the feasibility of improving the synchronisation of lambing after oestrus synchronisation and artificial insemination (AI). To this end, low doses of dexamethasone ...