Sfoglia per Soggetto "ribonucleoprotein"

A 40.7 kDa Rpp30/Rpp1 homologue is a protein subunit of Dictyostelium discoideum RNase P holoenzyme

Vourekas, A.; Kalavrizioti, D.; Zarkadis, I. K.; Spyroulias, G. A.; Stathopoulos, C.; Drainas, D. (2007)

RNase P is an essential and ubiquitous endonuclease that mediates the maturation of the 5' ends of all precursor tRNA molecules. The holoenzyme from Dictyostelium discoideum possesses RNA and protein subunits essential for ...

Anti-Ro52 antibody is highly prevalent and a marker of better prognosis in patients with ovarian cancer

Bogdanos D.P., Gkoutzourelas A., Papadopoulos V., Liaskos C., Patrikiou E., Tsigalou C., Saratziotis A., Hajiioannou J., Scheper T., Meyer W., Sakkas L.I., Papandreou C. (2021)

Background and Aims: Anti-Ro52 antibody (Ab) reactivity is highly prevalent in autoimmune rheumatic diseases (ARDs), mainly Sjögren's syndrome (SjS) and systemic lupus erythematosus (SLE), but also in other inflammatory ...

Anti-Ro60 Seropositivity Determines Anti-Ro52 Epitope Mapping in Patients With Systemic Sclerosis

Gkoutzourelas A., Liaskos C., Mytilinaiou M.G., Simopoulou T., Katsiari C., Tsirogianni A., Daoussis D., Scheper T., Meyer W., Bogdanos D.P., Sakkas L.I. (2018)

Epitope mapping of anti-Ro52 antibodies (Abs) has been extensively studied in patients with Sjögren's syndrome (SjS) and systemic lupus erythematosus (SLE). Comprehensive epitope mapping in systemic sclerosis (SSc), where ...

Major vault protein/lung resistance related protein: A novel biomarker for rheumatoid arthritis

Marinou D., Katsifis G., Barouta G., Liaskos C., Sakkas L.I., Tsakris A., Routsias J.G. (2021)

Objective Rheumatoid arthritis (RA) can lead to joint destruction and early institution of effective treatment can preserve joint function. Biomarkers can establish early diagnosis and predict effect of treatment. Vault ...

Nuclear localization of cytokeratin 8 and the O-linked N -acetylglucosamine-containing Epitope H in epithelial cells of infiltrating ductal breast carcinomas: A combination of immunogold and EDTA regressive staining methods

Havaki, S.; Voloudakis-Baltatzis, I.; Goutas, N.; Arvanitis, L. D.; Vassilaros, S. D.; Arvanitis, D. L.; Kittas, C.; Marinos, E. (2006)

In a previous study, the authors have shown cytokeratin 8 (CK8) and epitope H ultrastructural localization in breast cancer cell nuclei. Epitope H contains an O-linked N -acetylglucosamine (O-GlcNAc) residue in a specific ...

Prevalence of antinuclear antibodies and rheumatoid factor titers in dogs with arthritis secondary to leishmaniosis (Leishmania infantum)

Tsouloufi T.K., Theodorou K., Day M.J., Oikonomidis I.L., Kasabalis D., Mylonakis M.E., Saridomichelakis M.N., Kritsepi-Konstantinou M., Soubasis N. (2022)

Dogs with infectious arthritis may occasionally exhibit positive serum antinuclear antibody (ANA) and rheumatoid factor (RF) titers; however, relevant data are sparse for arthritis secondary to canine leishmaniosis (CanL) ...

RNase P: A promising molecular target for the development of new drugs

Tekos, A.; Stathopoulos, C.; Tsambaos, D.; Drainas, D. (2004)

RNase P is an ubiquitous and essential endonuclease in tRNA biogenesis, which generates the mature 5′-termini of tRNAs. RNase P activities have been identified in all three kingdoms of life (Bacteria, Archaea, Eukarya). ...

A study of antigen-specific anti-cytomegalovirus antibody reactivity in patients with systemic sclerosis and concomitant anti-Ro52 antibodies

Gkoutzourelas A., Liaskos C., Simopoulou T., Katsiari C., Efthymiou G., Scheper T., Meyer W., Tsirogianni A., Tsigalou C., Dardiotis E., Daoussis D., Sakkas L.I., Bogdanos D.P. (2020)

Anti-Ro52 autoantibody (autoAb), highly prevalent in Sjogren’s syndrome (SjS) and systemic lupus erythematosus (SLE), is also frequent in systemic sclerosis (SSc). Viral agents, such as human cytomegalovirus (HCMV), have ...

Targeted somatic mutagenesis through CRISPR/Cas9 ribonucleoprotein complexes in the olive fruit fly, Bactrocera oleae

Meccariello A., Tsoumani K.T., Gravina A., Primo P., Buonanno M., Mathiopoulos K.D., Saccone G. (2020)

The olive fruit fly, Bactrocera oleae (Diptera: Tephritidae), is the most destructive insect pest of olive cultivation, causing significant economic and production losses. Here, we present the establishment of the clustered ...