Sfoglia per Soggetto "metabolomics"
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Does centrifugation matter? Centrifugal force and spinning time alter the plasma metabolome
(2016)Background: Centrifugation is an indispensable procedure for plasma sample preparation, but applied conditions can vary between labs. Aim: Determine whether routinely used plasma centrifugation protocols (1500×g 10 min; ... -
Going retro: Oxidative stress biomarkers in modern redox biology
(2016)The field of redox biology is inherently intertwined with oxidative stress biomarkers. Oxidative stress biomarkers have been utilized for many different objectives. Our analysis indicates that oxidative stress biomarkers ... -
Insights into intrauterine growth restriction based on maternal and umbilical cord blood metabolomics
(2021)Intrauterine growth restriction (IUGR) is a fetal adverse condition, ascribed by limited oxygen and nutrient supply from the mother to the fetus. Management of IUGR is an ongoing challenge because of its connection with ... -
Metabolomic, hormonal and physiological responses to hypoglycemia versus euglycemia during exercise in adults with type 1 diabetes
(2020)Introduction This study sought to compare the metabolomic, hormonal and physiological responses to hypoglycemia versus euglycemia during exercise in adults with type 1 diabetes (T1D). Research design and methods Thirteen ... -
A metabolomics approach to uncover effects of different exercise modalities in type 1 diabetes
(2017)Introduction: Exercise-associated metabolism in type 1 diabetes (T1D) remains under-studied due to the complex interplay between exogenous insulin, counter-regulatory hormones and insulin-sensitivity. Objective: To identify ... -
Molecular diagnostic testing for primary biliary cholangitis
(2016)Introduction: A reliable liver autoimmune serology for the diagnosis of primary biliary cholangitis (PBC) is of particular importance. Recognition of patients at early stages and prompt treatment initiation may alter the ... -
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Overexpression of a biotic stress‐inducible pvgstu gene activates early protective responses in tobacco under combined heat and drought
(2021)Drought and heat stresses are major factors limiting crop growth and productivity, and their effect is more devastating when occurring concurrently. Plant glutathione transferases (GSTs) are differentially expressed in ... -
Quality control of serum and plasma by quantification of (4E,14Z)-sphingadienine-C18-1-phosphate uncovers common preanalytical errors during handling of whole blood
(2018)BACKGROUND: Nonadherence to standard operating procedures (SOPs) during handling and processing of whole blood is one of the most frequent causes affecting the quality of serum and plasma. Yet, the quality of blood samples ... -
Radiomics Represent a New Opportunity for Bariatric Surgery When Implemented in a Quality Improvement Context
(2022)[No abstract available] -
Targeted and global pharmacometabolomics in everolimus-based immunosuppression: association of co-medication and lysophosphatidylcholines with dose requirement
(2018)Introduction: The immunosuppressive therapy with everolimus (ERL) after heart transplantation is characterized by a narrow therapeutic window and a substantial variability in dose requirement. Factors explaining this ... -
Tryptophan-kynurenine profile in pediatric autoimmune hepatitis
(2019)The impairment of regulatory T cells (Tregs) is a characteristic feature of autoimmune hepatitis (AIH), and the degradation of tryptophan (Trp) to kynurenine (Kyn), by gamma interferon-induced indoleamine-2,3-dioxygenase-1 ... -
Untargeted Metabolomics Pilot Study Using UHPLC-qTOF MS Profile in Sows’ Urine Reveals Metabolites of Bladder Inflammation
(2022)Urinary tract infections (UTI) of sows (characterized by ascending infections of the urinary bladder (cyst), ureters, and renal pelvis), are major health issues with a significant economic impact to the swine industry. The ... -
Urinary Metabolomics From a Dose-Fractionated Polymyxin B Rat Model of Acute Kidney Injury
(2022)Background: Polymyxin B treatment is limited by kidney injury. This study sought to identify Polymyxin B-related urinary metabolomic profile modifications for early detection of polymyxin-associated nephrotoxicity. Methods: ... -
The use of various statistical methods for authenticity and detection of adulteration in fish and seafood
(2022)Various methodologies including genetic analyses, morphometrics, proteomics, lipidomics, metabolomics, etc. are now used or being developed to authenticate fish and seafood. Such techniques usually lead to the generation ... -
Why has metabolomics so far not managed to efficiently contribute to the improvement of assisted reproduction outcomes? The answer through a review of the best available current evidence
(2021)Metabolomics emerged to give clinicians the necessary information on the competence, in terms of physiology and function, of gametes, embryos, and the endometrium towards a targeted infertility treatment, namely, assisted ...