Sfoglia per Soggetto "disease course"
Items 1-20 di 99
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A 72-Year-Old Woman With Multiple Pulmonary Nodules and a History of Malignancy
(2021)A 72-year-old woman, nonsmoker, presented with approximately 2 months of nonproductive cough. The cough was initially intermittent, occurred more regularly during bedtime, but gradually became more frequent throughout the ... -
99mTc sestamibi as a prognostic factor of response to first-line therapy and outcome in patients with malignant lymphoma
(2013)INTRODUCTION: Resistance to chemotherapy poses a major problem in cancer patients. Although of multifactorial origin, some of the implicated mechanisms also interfere with Tc-MIBI uptake and retention in cancer cells. The ... -
Amino acid signatures in the HLA class II peptide-binding region associated with protection/susceptibility to the severe West Nile Virus disease
(2018)The MHC class II region in humans is highly polymorphic. Each MHC molecule is formed by an α and a β chain, produced by different genes, creating an antigen-binding groove. In the groove there are several pockets into which ... -
Anti-MCV antibodies predict radiographic progression in Greek patients with very early (<3 months duration) rheumatoid arthritis
(2017)This study aimed to assess the diagnostic and prognostic value of anti-mutated citrullinated vimentin (MCV) antibodies in very early rheumatoid arthritis (VERA) and in established rheumatoid arthritis (RA). Seventy-one ... -
Approaching reactive species in the frame of their clinical significance: A toxicological appraisal
(2020)Redox biology and toxicology are interrelated fields that have produced valuable evidence regarding the role and clinical significance of reactive species. These issues are analyzed herein by presenting 6 arguments, as ... -
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Ascending aortic intramural hematoma: current concepts
(2022)Purpose of review Type A intramural hematoma (TAIMH) is an acute aortic disease characterized by the presence of hematoma in the aortic media and involving the ascending aorta. Open repair seems to be the first treatment ... -
Assessment of knowledge, attitudes, and practices towards new coronavirus (SARS-CoV-2) of health care professionals in greece before the outbreak period
(2020)Introduction: The ongoing severe acute respiratory syndrome (SARS)-CoV-2 pandemic has expanded globally. The aim of the current study is to investigate the knowledge, attitudes, and practices (KAP) of health care professionals ... -
Association of antiviral therapy with reduced disease progression in chronic hepatitis b patients: Results from a nation-wide cohort study
(2016)Background and Aims: Although effective treatment in terms of inducing virological and biochemical response for chronic hepatitis B (CHB) is available, its effect on the clinical course of the disease has not yet been ... -
The autophagic response to oxidative stress in osteoarthritic chondrocytes is deregulated
(2018)It has been reported that oxidative stress (OS) is involved in the pathogenesis of osteoarthritis (OA) and that defective autophagy is accompanying this age-related disease. Moreover, it has been proposed that induction ... -
Baseline neurofilament levels in cerebrospinal fluid do not correlate with long-term prognosis in multiple sclerosis
(2022)Background: Multiple Sclerosis (MS) is the most common autoimmune disease of the central nervous system. Up to this day, no single accurate prognostic biomarker has been established in this disease. Neurofilaments are ... -
Body mass index in patients with Multiple Sclerosis: a meta-analysis
(2019)Background: The impact of nutrition and diet on the etiology of Multiple Sclerosis (MS) has been evaluated through a number of studies. Only a limited number reported findings on the association between body mass index ... -
Care of Patients with Alzheimer’s Disease
(2021)Introduction: Alzheimer’s disease is one of the irreversible dementias and leads to death. About 10% of people over 60 years and 20% of people over 80 will have Alzheimer’s sometime in their lives. In the case of Alzheimer’s ... -
Children with psoriasis and COVID-19: factors associated with an unfavourable COVID-19 course, and the impact of infection on disease progression (Chi-PsoCov registry)
(2022)Background: The COVID-19 pandemic has raised questions regarding the management of chronic skin diseases, especially in patients on systemic treatments. Data concerning the use of biologics in adults with psoriasis are ... -
Choroidal thickness and ocular growth in childhood
(2021)The involvement of the choroid in ocular growth regulation has been postulated in studies showing that refractive errors correlate with alterations in choroidal thickness (ChT). The advent of optical coherence tomography ... -
Clinical relevance of circulating autoantibodies in idiopathic pulmonary fibrosis; A NAt hard to break
(2022)Patients with idiopathic pulmonary fibrosis are screened for circulating autoantibodies as part of the initial interstitial lung disease workup. Management of seropositive idiopathic pulmonary fibrosis is currently considered ... -
COMP serum levels: A new non-invasive biomarker of liver fibrosis in patients with chronic viral hepatitis
(2017)Background & aims Recently we have shown that cartilage oligomeric matrix protein (COMP), a fibrillar collagen assembly regulator, is strongly associated with cirrhosis and hepatocellular carcinoma progression. Therefore, ... -
Complications of chronic peritoneal dialysis: The role of leptin
(2011)The use of peritoneal dialysis for patients with end stage renal disease is not widespread, mainly because of the complications of repeated peritoneal dialysis, such as peritonitis and peritoneal fibrosis. Leptin is a 16 ... -
Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: A systems biology based approach
(2010)To identify novel genes and pathways associated with AMD, we performed microarray gene expression and linkage analysis which implicated the candidate gene, retinoic acid receptor-related orphan receptor alpha (RORA, 15q). ...