Sfoglia per Soggetto "comet assay"
Items 1-10 di 10
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Benomyl, a benzimidazole fungicide, induces oxidative stress and apoptosis in neural cells
(2020)Fungicides are used in the agricultural sector against the harmful action of fungi, however they are potential toxic agents for the environment and the living organisms. Benomyl is a widely encountered benzimidazole fungicide ... -
Chapter 9: The Comet Assay: Clinical Applications
(2017)The single-cell gel electrophoresis (SCGE) or Comet assay is a technique widely employed in environmental and radiation toxicology as well as in cancer research with the aim of assessing DNA damage and repair by measuring ... -
DNA damage and repair efficiency in lymphocytes from schizophrenic patients
(2004)In the present study we examined schizophrenic patients' lymphocytes sensitivity to the effects of external factors, such as hydrogen peroxide and gamma-irradiation and also their repair efficiency with the comet assay. ... -
DNA damage in a human population affected by chronic psychogenic stress
(2003)The effects of chronic psychogenic stress on the expression of DNA damage and cellular response to the damage were investigated. Using the comet assay, basal DNA damage was found to be similar in lymphocytes of both affected ... -
Effects of pesticides on occupationally exposed humans
(2006)Pesticides are known to contain numerous genotoxic compounds; however, genotoxicity biomonitoring studies of workers occupationally exposed to pesticides have produced variable results. In this study, we employed the Comet ... -
Effects of pulsed electric fields on DNA of human lymphocytes
(2006)The effects of pulsed electric fields of low frequency (50 Hz) on DNA of human lymphocytes were investigated. The influence of additional external factors, such as hydrogen peroxide (H2O2) and gamma-irradiation, as well ... -
Excision of an oxidative DNA lesion (8-oxo-deoxyguanosine) in Mytilus edulis populations from two sites in the eastern Irish Sea
(2008)Mussels (Mytilus edulis) from the urban/industrialised site of New Brighton, Merseyside, UK and the reference site of Llandudno, North Wales, UK were collected at various time-points in 2005-2006. The excision capacity of ... -
Investigation of the Genotoxic Effect of Pesticides on Greenhouse Workers' Lymphocytes
(2009)In the present study, the genotoxic effects of commonly applied pesticides were evaluated using the alkaline comet assay (pH > 13). The amount of DNA damage (% DNA in tail) in peripheral lymphocytes of 49 male agricultural ... -
The metabolism of imidacloprid by aldehyde oxidase contributes to its clastogenic effect in New Zealand rabbits
(2018)Imidacloprid (IMI) is a systemic, chloro-nicotinyl insecticide classified in Regulation N° 1272/2008 of the European Commision as “harmful if swallowed and very toxic to aquatic life, with long-lasting effects”. IMI is ... -
The sesquiterpenoid valerenic acid protects neuronal cells from the detrimental effects of the fungicide benomyl on apoptosis and DNA oxidation
(2022)Background: Valerenic acid (VA), a sesquiterpenoid of the plant Valeriana officinalis, has attracted attention of the research community due to its potential positive role against neurodegenerative diseases induced by ...