Sfoglia per Soggetto "RNA interference"

Decoding the reproductive system of the olive fruit fly, Bactrocera oleae

Gregoriou M.-E., Reczko M., Kakani E.G., Tsoumani K.T., Mathiopoulos K.D. (2021)

In most diploid organisms, mating is a prerequisite for reproduction and, thus, critical to the maintenance of their population and the perpetuation of the species. Besides the importance of understanding the fundamentals ...

DIANA-LncBase v3: Indexing experimentally supported miRNA targets on non-coding transcripts

Karagkouni D., Paraskevopoulou M.D., Tastsoglou S., Skoufos G., Karavangeli A., Pierros V., Zacharopoulou E., Hatzigeorgiou A.G. (2020)

DIANA-LncBase v3.0 (www.microrna.gr/LncBase) is a reference repository with experimentally supported miRNA targets on non-coding transcripts. Its third version provides approximately half a million entries, corresponding ...

Enhanced expression of miR-21 and miR-150 is a feature of anti-mitochondrial antibody-negative primary biliary cholangitis

Wasik U., Kempinska-Podhorodecka A., Bogdanos D.P., Milkiewicz P., Milkiewicz M. (2020)

Background & Aims: Anti-mitochondrial-autoantibodies (AMA) remain a hallmark of Primary Biliary Cholangitis (PBC) however approximately 10% of patients test negative for these antibodies. They do not differ in terms of ...

Enhancer of rudimentary homologue interacts with scaffold attachment factor B at the nuclear matrix to regulate SR protein phosphorylation

Drakouli S., Lyberopoulou A., Papathanassiou M., Mylonis I., Georgatsou E. (2017)

Scaffold attachment factor B1 (SAFB1) is an integral component of the nuclear matrix of vertebrate cells. It binds to DNA on scaffold/matrix attachment region elements, as well as to RNA and a multitude of different proteins, ...

The expression of myeloproliferative neoplasm-associated calreticulin variants depends on the functionality of er-associated degradation

Mansier O., Prouzet-Mauléon V., Jégou G., Barroso K., Pelizzari Raymundo D., Chauveau A., Pierre-Yves D., Lagarde V., Turcq B., Jean-Max P., Jean-François V., James C., Praloran V., Voutetakis K., Chatziioannou A., François-Xavier M., Chevet E., Lippert E. (2019)

Background: Mutations in CALR observed in myeloproliferative neoplasms (MPN) were recently shown to be pathogenic via their interaction with MPL and the subsequent activation of the Janus Kinase – Signal Transducer and ...

Genetically modified organism-free RNA interference: Exogenous application of RNA molecules in plants1[open]

Dalakouras A., Wassenegger M., Dadami E., Ganopoulos I., Pappas M.L., Papadopoulou K. (2020)

Since its discovery more than 20 years ago, RNA interference (RNAi) has been extensively used in crop protection platforms. So far, RNAi approaches have been conventionally based on the use of transgenic plants expressing ...

Lotus SHAGGY-like kinase 1 is required to suppress nodulation in Lotus japonicus

Garagounis C., Tsikou D., Plitsi P.K., Psarrakou I.S., Avramidou M., Stedel C., Anagnostou M., Georgopoulou M.E., Papadopoulou K.K. (2019)

Glycogen synthase kinase/SHAGGY-like kinases (SKs) are a highly conserved family of signaling proteins that participate in many developmental, cell-differentiation, and metabolic signaling pathways in plants and animals. ...

Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests

Meccariello A., Salvemini M., Primo P., Hall B., Koskinioti P., Dalíková M., Gravina A., Gucciardino M.A., Forlenza F., Gregoriou M.-E., Ippolito D., Monti S.M., Petrella V., Perrotta M.M., Schmeing S., Ruggiero A., Scolari F., Giordano E., Tsoumani K.T., Marec F., Windbichler N., Arunkumar K.P., Bourtzis K., Mathiopoulos K.D., Ragoussis J., Vitagliano L., Tu Z., Papathanos P.A., Robinson M.D., Saccone G. (2019)

In insects, rapidly evolving primary sex-determining signals are transduced by a conserved regulatory module controlling sexual differentiation. In the agricultural pest Ceratitis capitata (Mediterranean fruit fly, or ...