Sfoglia per Soggetto "PROTEINS"
Items 1-20 di 27
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ABNORMAL EXPRESSION OF C3ORF9 GENE IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES
(2009)Myelodysplastic Syndrome (MDS) cells present genetic instability and dysregulation of the gene C3ORF9, which was isolated from an MDS cDNA library and codes for a putative protein. We studied the expression of C3ORF9 in ... -
Albumin possesses intrinsic enolase activity towards dihydrotestosterone which can differentiate benign from malignant breast tumors
(1999)Serum albumin was found to possess enolase activity towards the dihydrotestesterone (DHT) molecule, converting it from its 3-keto to 3-enol form. This activity was accompanied by albumin during all stages of purification, ... -
Anti-mitochondrial antibody immunofluorescent titres correlate with the number and intensity of immunoblot-detected mitochondrial bands in patients with primary biliary cirrhosis
(2007)Background: Primary biliary cirrhosis (PBC)-specific anti-mitochondrial antibodies (AMA), routinely detected by indirect immunofluoresnce, immunofix various mitochondrial antigens by immunoblot (IB). We have investigated ... -
Cannabinoid 1 receptor-dependent transactivation of fibroblast growth factor receptor 1 emanates from lipid rafts and amplifies extracellular signal-regulated kinase 1/2 activation in embryonic cortical neurons
(2011)G-protein coupled receptors may mediate their effects on neuronal growth and differentiation through activation of extracellular signal-regulated kinases 1/2 (ERK1/2), often elicited by transactivation of growth factor ... -
CER1 gene variations associated with bone mineral density, bone markers, and early menopause in postmenopausal women
(2013)Background: Osteoporosis has a multifactorial pathogenesis characterized by a combination of low bone mass and increased fragility. In our study, we focused on the effects of polymorphisms in CER1 and DKK1 genes, recently ... -
CHANGES IN CYTOCHROME C OXIDASE (CCO) AND LACTATE DEHYDROGENASE (LDH) ENZYME ACTIVITY OF THE WHITE EPAXIAL MUSCLE TISUE OF SEA BAS (DICENTRARCHUS LABRAX L.) AS SHELF-LIFE PREDICTIVE INDICES DURING ICE-STORAGE
(2010)Fish freshness can be evaluated by sensory, physical and biochemical parameters. The purpose of the present work was to evaluate the potential utilisation of enzyme activity changes as indicators of shelf life in ice-stored ... -
A Comprehensive Phylogenetic Analysis of Deadenylases
(2013)Deadenylases catalyze the shortening of the poly(A) tail at the messenger ribonucleic acid (mRNA) 3'-end in eukaryotes. Therefore, these enzymes influence mRNA decay, and constitute a major emerging group of promising ... -
Correlation Between Cyclin B1 Immunostaining in Cervical Biopsies and HPV Detection by PCR
(2009)In recent years, experimental data on the roles of viruses and cyclin B1 in G2/M arrest has accumulated. The aim of our study Was to immunohistochemically examine a series of cervical squamous intraepithelial lesions for ... -
Differential effects of xanthine oxidase inhibition and exercise on albumin concentration in rat tissues
(2010)Albumin is a protein present in almost all kinds of mammalian cells. It has binding sites for several molecules, and possesses antioxidant and other important properties. The aim of this study was to examine the effects ... -
Effects of xanthine oxidase inhibition on oxidative stress and swimming performance in rats
(2008)The aim of this study was to examine the effect of allopurinol, a xanthine oxidase inhibitor, on oxidative stress and physical performance after swimming until exhaustion in rats. Blood and gastrocnemius muscle samples ... -
The expression of the O-linked N-acetylglucosamine containing epitope H in the gemistocytic, pilocytic and subependymal giant cell astrocytomas
(2009)The epitope H contains an O-linked N-acetylglucosamine residue in a specific conformation and/or environment recognized by the monoclonal antibody H. It has previously been shown that the epitope H is present in several ... -
Genome-Wide Analysis of the Phosphoinositide Kinome from Two Ciliates Reveals Novel Evolutionary Links for Phosphoinositide Kinases in Eukaryotic Cells
(2013)Background: The complexity of phosphoinositide signaling in higher eukaryotes is partly due to expansion of specific families and types of phosphoinositide kinases (PIKs) that can generate all phosphoinositides via multiple ... -
Immunohistochemical expression of extracellular matrix components tenascin, fibronectin, collagen type IV and laminin in breast cancer: their prognostic value and role in tumour invasion and progression
(2002)The immunohistochemical expression of the extracellular matrix (ECM) components tenascin (TN), fibronectin (FN), collagen type IV (Coll) and laminin (LN), and their possible relationships were studied in a series of 134 ... -
Immunological mimic features of visceral leishmaniasis may systemic lupus erythematosus
(2008)Objective: Visceral leishmaniasis (VL), caused by the intracellular parasite Leishmania, can present with fever, splenomegaly, pancytopenias, hypergammaglobulinemia, and autoantibody production. These features may mimic ... -
In vivo cell kinetics in breast carcinogenesis
(2001)Background: Disruption of the balance between apoptosis and proliferation is considered to be an important factor in the development and progression of tumours. In the present study we determined the in vivo cell kinetics ... -
Investigation of in vivo toxicity of hydroxylamine sulfate and the efficiency of intoxication treatment by alpha-tocopherol acetate and methylene blue
(2013)Objectives: Investigation of hydroxylamine sulfate toxicity mechanism in vivo and estimation of alpha-tocopherol acetate and methylene blue efficiency in poisoning treatments. Methods: In vivo experiments were conducted ... -
Large-Scale Analysis of Association Between GDF5 and FRZB Variants and Osteoarthritis of the Hip, Knee, and Hand
(2009)Objective. GDF5 and FRZB have been proposed as genetic loci conferring susceptibility to osteoarthritis (OA); however, the results of several studies investigating the association of OA with the rs143383 polymorphism of ... -
Low expression of p27 protein combined with altered p53 and Rb/p16 expression status is associated with increased expression of cyclin A and cyclin B1 in diffuse large B-cell lymphomas
(2001)The expression of the cyclin-dependent kinase inhibitor (CDKI) p27 protein was investigated in relation to (1) the expression of the cell cycle regulators p53, Rb and p16 and (2) the proliferation profile as determined by ... -
Mapping interleukin enhancer binding factor 2 gene (ILF2) to human chromosome 1 (1q11-qter and 1p11-p12) by polymerase chain reaction amplification of human rodent somatic cell hybrid DNA templates
(1996)Interleukin-2 (IL-2) is the first lymphokine secreted following T cell activation, Several transcription factors regulate IL-2 gene expression, including the nuclear factor of activated T cells (NFAT), NFAT acts at the ... -
A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip
(2014)Objectives Osteoarthritis (OA) is the most common form of arthritis with a clear genetic component. To identify novel loci associated with hip OA we performed a meta-analysis of genome-wide association studies (GWAS) on ...