Sfoglia per Soggetto "DESIGN"
Items 1-20 di 45
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A 1 V CMOS programmable accurate charge pump with wide output voltage range
(2011)A 1 V, programmable, accurate, high speed, single-ended charge pump is proposed, suitable for low voltage PLLs. It is designed in TSMC 90-nm digital CMOS process and it consists of four switches in a current steering ... -
Automated context aggregation and file annotation for PAN-based computing
(2007)This paper presents a method for automatically annotating files created on portable devices with contextual metadata. We achieve this through the combination of two system components. One is a context dissemination mechanism ... -
Baseline characteristics of the 4011 patients recruited into the 'Efficacy of Nitric Oxide in Stroke' (ENOS) trial
(2014)Background High blood pressure is common in acute stroke and associated with a worse functional outcome. Many patients who present with acute stroke are taking prescribed antihypertensive therapy before their stroke. Aims ... -
The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: A new class of inhibitors
(2010)Glycogen phosphorylase (GP) is a promising target for the treatment of type 2 diabetes. In the process of structure based drug design for GP, a group of 15 aromatic aldehyde 4-(beta-D-glucopyranosyl) thiosemicarbazones ... -
The binding of C5-alkynyl and alkylfurano 2,3-d pyrimidine glucopyranonucleosides to glycogen phosphorylase b: Synthesis, biochemical and biological assessment
(2012)C5-alkynyl and allcylfurano[2,3-d]pyrimidine glucopyranonucleosides have been synthesized and studied as inhibitors of glycogen phosphorylase b (GPb). Kinetic experiments have shown that most of these compounds were low ... -
Catch the kinase conformer
(2006)Protein kinases exist in inactive and active states, but little attention has been paid to which state is or should be the target in drug discovery efforts. In this issue of Chemistry & Biology, Okram et al. [1] tackle ... -
Comparative calculation of irrigation networks using Labye's method, the linear programming method and a simplified nonlinear method
(2010)The designating factors in the design of branched irrigation networks are the cost of pipes and the cost of pumping. They both depend directly on the hydraulic pump head. It is mandatory for this reason to calculate the ... -
Constructivist Learning and Teaching of Optics Concepts Using ICT Tools in Greek Primary School: A Pilot Study
(2009)This pilot study documents the design and evaluation results of an innovative teaching approach with the use of ICT regarding the optics concepts of light reflection and diffusion, and vision in Greek primary school. First ... -
Deployment Strategies and Energy Efficiency of Cellular Networks
(2012)The energy efficiency of cellular networks is explored for different network deployment strategies and traffic conditions. The total network power consumption and the ratios Watts/kbps, Watts/user are used as metrics to ... -
Efficient soluble expression of active recombinant human cyclin A2 mediated by E. coli molecular chaperones
(2015)Bacterial expression of human proteins continues to present a critical challenge in protein crystallography and drug design. While human cyclin A constructs have been extensively characterized in complex with cyclin dependent ... -
Energy analysis of an improved concept of integrated PV panels in an office building in central Greece
(2011)During the last decade, steel constructions with glazed facades became popular for commercial buildings in Greece. Moreover, expensive metal, natural stone, marble, ceramic, granite as well as special glass is employed for ... -
Enhancing Differential Evolution Utilizing Proximity-Based Mutation Operators
(2011)Differential evolution is a very popular optimization algorithm and considerable research has been devoted to the development of efficient search operators. Motivated by the different manner in which various search operators ... -
Finite element analysis of buried steel pipelines under strike-slip fault displacements
(2010)The present paper investigates the mechanical behavior of buried steel pipelines, crossing an active strike-slip tectonic fault The fault is normal to the pipeline direction and moves in the horizontal direction, causing ... -
Full and part load exergetic analysis of a hybrid micro gas turbine fuel cell system based on existing components
(2012)The paper deals with the examination of a hybrid system consisting of a pre-commercially available high temperature solid oxide fuel cell and an existing recuperated microturbine. The irreversibilities and thermodynamic ... -
Fully Digital FPGA-Based Data Acquisition System for Dual Head PET Detectors
(2014)We present the development of a new fully digital, flexible, cost-efficient data acquisition system (DAQ) suitable for dual head Positron Emission Tomography (PET) scanners for small animal imaging applications. A free-running ... -
A fuzzy decision tree-based SVM classifier for assessing osteoarthritis severity using ground reaction force measurements
(2010)A novel fuzzy decision tree-based SVM (FDT-SVM) classifier is proposed in this paper, to distinguish between asymptotic (AS) and osteoarthritis (OA) knee gait patterns and to investigate OA severity using 3-D ground reaction ... -
Glycogen Phosphorylase as a Target for Type 2 Diabetes: Synthetic, Biochemical, Structural and Computational Evaluation of Novel N-acyl-N '-(beta-D-glucopyranosyl) Urea Inhibitors
(2015)Glycogen phosphorylase (GP), a validated target for the development of anti-hyperglycaemic agents, has been targeted for the design of novel glycopyranosylamine inhibitors. Exploiting the two most potent inhibitors from ... -
A heuristic algorithm for the buffer allocation in unreliable unbalanced production lines
(2001)In this work we investigate the buffer allocation problem (BAP) in short unbalanced production lines consisting of up to six machines that are subject to breakdowns. Times to failure are assumed exponential whereas service ... -
Hexavalent chromium release from lignite fly ash and related ecotoxic effects
(2013)Hexavalent chromium Cr(VI) is a pollutant of immense concern due to its high mobility to water sources and highly toxic properties. In most cases, Cr(VI) could be released from lignite fly ash in aquatic environment when ...