Sfoglia per Soggetto "Crocus"
Items 1-13 di 13
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Constituents of saffron (Crocus sativus L.) as potential candidates for the treatment of anxiety disorders and schizophrenia
(2016)Anxiety disorders and schizophrenia are common public health issues. The dried stigma of the plant Crocus sativus L., (C. sativus) commonly known as saffron are used in folk medicine for various purposes. Several lines of ... -
Crocins, the active constituents of Crocus sativus L., counteracted apomorphine-induced performance deficits in the novel object recognition task, but not novel object location task, in rats
(2017)Schizophrenia is a chronic mental disease that affects nearly 1% of the population worldwide. Several lines of evidence suggest that the dopaminergic (DAergic) system might be compromised in schizophrenia. Specifically, ... -
Crocins, the bioactive components of crocus sativus l., counteract the disrupting effects of anesthetic ketamine on memory in rats
(2021)Consistent experimental evidence suggests that anesthetic doses of the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist ketamine cause severe memory impairments in rodents. Crocins are among the various ... -
Crocus sativus l. Extract and its constituents: Chemistry, pharmacology and therapeutic potential
(2021)[No abstract available] -
Crocus sativus L. extracts and its constituents crocins and safranal; Potential candidates for schizophrenia treatment?
(2021)Schizophrenia is a chronic mental devastating disease. Current therapy suffers from various limitations including low efficacy and serious side effects. Thus, there is an urgent necessity to develop new antipsychotics with ... -
Crocus sativus L. extracts antagonize memory impairments in different behavioural tasks in the rat
(2006)The effects of extracts of Crocus sativus L. (CSE), on memory were investigated in the rat by using the object recognition and the step-through passive avoidance task. In the first study, post-training administration of ... -
Effect of crocus sativus (Saffron) intake on top of standard treatment, on disease outcomes and comorbidities in patients with rheumatic diseases: Synthesis without meta-analysis (SWiM) and level of adherence to the CONSORT statement for randomized controlled trials delivering herbal medicine interventions
(2021)Rheumatic diseases (RDs) are often complicated by chronic symptoms and frequent sideeffects associated with their treatment. Saffron, a spice derived from the Crocus sativus L. flower, is a popular complementary and ... -
Effects of short-term saffron (Crocus sativus L.) intake on the in vivo activities of xenobiotic metabolizing enzymes in healthy volunteers
(2019)Crocus sativus L., a perennial plant grown mainly around the Mediterranean and Iran, has many medicinal properties including anti-inflammatory, anti-depressive and cancer preventing properties. Aqueous herbal extracts may ... -
Effects of the active constituents of Crocus sativus L. crocins and their combination with memantine on recognition memory in rats
(2018)Crocus sativus L., is a plant cultivated in many countries of the world. Crocins are among the active constituents of C. sativus and their implication in cognition has been proposed. The present study was designed to ... -
The gabaa-benzodiazepine receptor antagonist flumazenil abolishes the anxiolytic effects of the active constituents of crocus sativus l. Crocins in rats
(2020)Anxiety is a chronic severe psychiatric disorder. Crocins are among the various bioactive components of the plant Crocus sativus L. (Iridaceae) and their implication in anxiety is well-documented. However, which is the ... -
Mechanistic insights on the effect of crocin, an active ingredient of saffron, on atherosclerosis in apolipoprotein E knockout mice
(2022)Background We investigated the effect of crocin treatment on atherosclerosis and serum lipids in apolipoprotein E knockout (ApoE-/-) mice, focusing on the expression of endothelial nitric oxide synthase (eNOS) and ... -
Petals of Crocus sativus L. as a potential source of the antioxidants crocin and kaempferol
(2015)Saffron from the province of L'Aquila, in the Abruzzo region of Italy, is highly prized and has been awarded a formal recognition by the European Union with EU Protected Designation of Origin (PDO) status. Despite this, ... -
Recent Advances on the Anticancer Properties of Saffron (Crocus sativus L.) and Its Major Constituents
(2021)Cancer is the second leading cause of death globally with an estimated 9.6 million deaths in 2018 and a sustained rise in its incidence in both developing and developed countries. According to the WHO, about 1 in 6 deaths ...