Sfoglia per Autore "Vlassi, M."
Items 1-2 di 2
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Competitive Inhibition of Human Poly(A)-Specific Ribonuclease (PARN) by Synthetic Fluoro-Pyranosyl Nucleosides
Balatsos, N. A. A.; Vlachakis, D.; Maragozidis, P.; Manta, S.; Anastasakis, D.; Kyritsis, A.; Vlassi, M.; Komiotis, D.; Stathopoulos, C. (2009)Poly(A)-specific ribonuclease (PARN) is a cap-interacting deadenylase that mediates, together with other exonucleases, the eukaryotic mRNA turnover and thus is actively involved in the regulation of gene expression. ... -
Kinetic and in silico analysis of the slow-binding inhibition of human poly(A)-specific ribonuclease (PARN) by novel nucleoside analogues
Balatsos, N.; Vlachakis, D.; Chatzigeorgiou, V.; Manta, S.; Komiotis, D.; Vlassi, M.; Stathopoulos, C. (2012)Poly(A)-specific ribonuclease (PARN) is a 3'-exoribonuclease that efficiently degrades poly(A) tails and regulates, in part, mRNA turnover rates. We have previously reported that adenosine- and cytosine-based glucopyranosyl ...