Sfoglia per Autore "Tzouvelekis, L. S."
Items 1-12 di 12
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Characterization of Metallo-beta-Lactamase VIM-27, an A57S Mutant of VIM-1 Associated with Klebsiella pneumoniae ST147
Papagiannitsis, C. C.; Kotsakis, S. D.; Petinaki, E.; Vatopoulos, A. C.; Tzelepi, E.; Miriagou, V.; Tzouvelekis, L. S. (2011)VIM-27 metallo-beta-lactamase, an Ala(57) -> Ser variant of VIM-1, was identified in three Klebsiella pneumoniae isolates belonging to sequence type 147. bla(VIM-27) was part of a class 1 integron carried by non-self-transferable ... -
Confronting carbapenemase-producing Klebsiella pneumoniae
Markogiannakis, A.; Tzouvelekis, L. S.; Psichogiou, M.; Petinaki, E.; Daikos, G. L. (2013)The ongoing spread of carbapenemase-producing (CP) multidrug-resistant enterobacteria, primarily Klebsiella pneumoniae, has undoubtedly caused a public health crisis of unprecedented dimensions. The scientific community ... -
Effects of the Val211Gly substitution on molecular dynamics of the CMY-2 cephalosporinase: Implications on hydrolysis of expanded-spectrum cephalosporins
Kotsakis, S. D.; Tzouvelekis, L. S.; Petinaki, E.; Tzelepi, E.; Miriagou, V. (2011)CMY-30, a naturally occurring class C beta-lactamase differing from the Citrobacter freundii-derived CMY-2 by a Val211Gly substitution in the X-loop, exhibits increased hydrolytic efficiency against ceftazidime and cefotaxime. ... -
Emergence of Escherichia coli sequence type 410 (ST410) with KPC-2 beta-lactamase
Mavroidi, A.; Miriagou, V.; Malli, E.; Stefos, A.; Dalekos, G. N.; Tzouvelekis, L. S.; Petinaki, E. (2012)Fifteen carbapenem-non-susceptible Escherichia coli isolates obtained during the period May 2010 to April 2011 in a hospital and a long-term care facility (LTCF) in Larissa (Central Greece) were investigated. Minimum ... -
Evaluation of an anti-PBP 2a slide latex agglutination test in coagulase-negative staphylococci isolated in Greek hospitals
Petinaki, E.; Miriagou, V.; Tzouvelekis, L. S.; Hatzi, F.; Legakis, N. J.; Maniatis, A. N. (2002)Oxacillin resistance was examined in 258 coagulase-negative staphylococci from Greek hospitals. mecA DNA was detected in 168 isolates, which were also resistant to oxacillin by agar dilution and disk diffusion, according ... -
Interactions of Oximino-Substituted Boronic Acids and beta-Lactams with the CMY-2-Derived Extended-Spectrum Cephalosporinases CMY-30 and CMY-42
Kotsakis, S. D.; Caselli, E.; Tzouvelekis, L. S.; Petinaki, E.; Prati, F.; Miriagou, V. (2013)CMY-30 and CMY-42 are extended-spectrum (ES) derivatives of CMY-2. ES characteristics are due to substitutions of Gly (CMY-30) and Ser (CMY-42) for Val211 in the Omega-loop. To characterize the effects of 211 substitutions, ... -
Methicillin-resistant Staphylococcus aureus in the hospitals of Central Greece
Petinaki, E.; Miriagou, V.; Tzouvelekis, L. S.; Pournaras, S.; Hatzi, F.; Kontos, F.; Maniati, M.; Maniatis, A. N. (2001)A total of 250 consecutive Staphylococcus aureus clinical isolates were collected during the period 1999-2000 from the five major hospitals of the district of Thessaly (Central Greece). Thirty seven (14.8%) of the isolates ... -
Mupirocin resistance in Staphylococcus aureus from Greek hospitals
Maniatis, N.; Agel, A.; Legakis, N. J.; Tzouvelekis, L. S. (2001) -
Novel variant (bla(VlM-4)) of the metallo-beta-lactamase gene bla(VIM-1) in a clinical strain of Pseudomonas aeruginosa
Pournaras, S.; Tsakris, A.; Maniati, M.; Tzouvelekis, L. S.; Maniatis, A. N. (2002)A Pseudomonas aeruginosa isolate highly resistant to carbapenems was collected from a patient with post-surgical cerebrospinal infection in Greece. The isolate carried a class I integron that contained as a sole cassette ... -
VIM-1 metallo-beta-lactamase in Acinetobacter baumannii
Tsakris, A.; Ikonomidis, A.; Pournaras, S.; Tzouvelekis, L. S.; Sofianou, D.; Legakis, N. J.; Maniatis, A. N. (2006)In 2004 and 2005, 5 metallo-beta-lactamase (MBL)-positive Acinetobacter baumannii isolates were found in 2 Greek hospitals. Isolates were unrelated and carried bla(VIM-1) in a class 1 integron; bla(OXA-51-) and bla(OXA-58-like) ... -
VIM-1 metallo-β-lactamase in Acinetobacter baumannii
Tsakris, A.; Ikonomidis, A.; Pournaras, S.; Tzouvelekis, L. S.; Sofianou, D.; Legakis, N. J.; Maniatis, A. N. (2006)In 2004 and 2005, 5 metallo-β-lactamase (MBL)-positive Acinetobacter baumannii isolates were found in 2 Greek hospitals. Isolates were unrelated and carried blaVIM-1 in a class 1 integron; blaOXA-51- and blaOXA-58-like ... -
VIM-12, a novel plasmid-mediated metallo-β-lactamase from Klebsiella pneumoniae that resembles a VIM-1/VIM-2 hybrid
Pournaras, S.; Ikonomidis, A.; Tzouvelekis, L. S.; Tokatlidou, D.; Spanakis, N.; Maniatis, A. N.; Legakis, N. J.; Tsakris, A. (2005)A transferable plasmid from Klebsiella pneumoniae carried a class 1 integron containing blaVIM-12, a novel blaVIM-type gene, flanked by two copies of aacA7. blaVIM-12 was clustered between bla-VIM-1 and bla-VIM-2 and ...