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Mechanisms of Disease: the role of immune cells in the pathogenesis of systemic sclerosis
(2006)Systemic sclerosis is characterized by extensive fibrosis, microvascular stenosis and autoantibody production. All three characteristics can be accounted for by activation of cells of the immune system. Activation of T ... -
New developments in the pathogenesis of systemic sclerosis
(2005)Systemic sclerosis (SSc) is characterized by extensive fibrosis, vasculopathy and activation of the immune system. Fibrosis can be caused by profibrotic cytokines, such as transforming growth factor-beta (TGF beta), ...