Parcourir par sujet "hydroxymethylglutaryl coenzyme A reductase inhibitor"

A 72-Year-Old Woman With Multiple Pulmonary Nodules and a History of Malignancy

Perlepe G., Karetsi E., Papamichali R., Papadopoulos D., Chevas A., Gourgoulianis K.I. (2021)

A 72-year-old woman, nonsmoker, presented with approximately 2 months of nonproductive cough. The cough was initially intermittent, occurred more regularly during bedtime, but gradually became more frequent throughout the ...

Adherence to oral anticoagulation in ischemic stroke patients with atrial fibrillation

Tiili P., Leventis I., Kinnunen J., Svedjebäck I., Lehto M., Karagkiozi E., Sagris D., Ntaios G., Putaala J. (2021)

Background: Non-vitamin K antagonist oral anticoagulants (NOAC) have superior safety and comparable efficacy profile compared to vitamin-K antagonists (VKAs), with more convenient dosing schemes. However, issues with ...

Carotid artery plaque echomorphology and its association with histopathologic characteristics

Spanos K., Tzorbatzoglou I., Lazari P., Maras D., Giannoukas A.D. (2018)

Objective: The aim of the study was to determine the association of ultrasonic texture features (severity of stenosis, grey scale median, plaque area, juxtaluminal black area [JBA], and discrete white areas) previously ...

Cholesterol metabolism related genes in osteoarthritis

Papathanasiou I., Anastasopoulou L., Tsezou A. (2021)

Cholesterol homeostasis plays a significant role in skeletal development and the dysregulation of cholesterol-related mechanism has been shown to be involved in the development of cartilage diseases including osteoarthritis ...

Clinical outcomes and neuroimaging profiles in nondisabled patients with anticoagulant-related intracerebral hemorrhage

Lioutas V.-A., Goyal N., Katsanos A.H., Krogias C., Zand R., Sharma V.K., Varelas P., Malhotra K., Paciaroni M., Sharaf A., Chang J., Karapanayiotides T., Kargiotis O., Pappa A., Mai J., Pandhi A., Schroeder C., Tsantes A., Mehta C., Kerro A., Khan A., Mitsias P.D., Selim M.H., Alexandrov A.V., Tsivgoulis G. (2018)

Background and Purpose: The aim of this study was to prospectively validate our prior findings of smaller hematoma volume and lesser neurological deficit in nonvitamin K oral anticoagulant (NOAC) compared with Vitamin K ...

A cohort of fat enough but malnourished hemodialysis patients

Eleftheriadis T., Liakopoulos V., Stefanidis I. (2020)

[No abstract available]

Consensus statements and recommendations from the ESO-Karolinska Stroke Update Conference, Stockholm 11–13 November 2018

Ahmed N., Audebert H., Turc G., Cordonnier C., Christensen H., Sacco S., Sandset E.C., Ntaios G., Charidimou A., Toni D., Pristipino C., Köhrmann M., Kuramatsu J.B., Thomalla G., Mikulik R., Ford G.A., Martí-Fàbregas J., Fischer U., Thoren M., Lundström E., Rinkel G.J.E., Worp H.B.V.D., Matusevicius M., Tsivgoulis G., Milionis H., Rubiera M., Hart R., Moreira T., Lantz M., Sjöstrand C., Andersen G., Schellinger P., Kostulas K., Sunnerhagen K.S., Keselman B., Korompoki E., Purrucker J., Khatri P., Whiteley W., Berge E., Mazya M., Dippel D.W.J., Mustanoja S., Rasmussen M., Söderqvist Å.K., Escudero-Martínez I., Steiner T. (2019)

The purpose of the European Stroke Organisation–Karolinska Stroke Update Conference is to provide updates on recent stroke therapy research and to give an opportunity for the participants to discuss how these results may ...

A critical appraisal of the pharmacological management of stable angina

Farmakis D., Xanthopoulos A., Triposkiadis F. (2021)

The once dominant plaque-centric model of the pathophysiology and management of coronary artery disease (CAD) has long been questioned by a bulk of experimental and clinical evidence suggesting, among others, that coronary ...

Diagnosis and management of chronic coronary artery disease

Triposkiadis, F.; Starling, R. C.; Stefanadis, C. (2007)

Coronary artery disease (CAD) usually coexists with atherosclerosis of other arterial trees and is accelerated by several risk factors. It may remain asymptomatic for a long period affecting the vessel wall with no lumen ...

Direct oral anticoagulant-vs Vitamin K antagonist-related nontraumatic intracerebral hemorrhage

Tsivgoulis G., Lioutas V.-A., Varelas P., Katsanos A.H., Goyal N., Mikulik R., Barlinn K., Krogias C., Sharma V.K., Vadikolias K., Dardiotis E., Karapanayiotides T., Pappa A., Zompola C., Triantafyllou S., Kargiotis O., Ioakeimidis M., Giannopoulos S., Kerro A., Tsantes A., Mehta C., Jones M., Schroeder C., Norton C., Bonakis A., Chang J., Alexandrov A.W., Mitsias P., Alexandrov A.V. (2017)

Objective: To compare the neuroimaging profile and clinical outcomes among patients with intracerebral hemorrhage (ICH) related to use of vitamin K antagonists (VKAs) or direct oral anticoagulants (DOACs) for nonvalvular ...

Do the Kinetics of Antibody Responses Predict Clinical Outcome in Hospitalized Patients With Moderate-to-Severe COVID-19?

Pavlidis G., Kampolis C.F., Perlepe G., Pagonis A., Maniotis C., Koullias E., Kranidioti H., Kyritsis A., Pavlou E., Sinis S., Pirounaki M., Vassilopoulos D., Gourgoulianis K., Pantazopoulos I. (2022)

Background/Aim: The relationship between the kinetics of antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the severity of Coronavirus Disease 2019 (COVID-19) is poorly understood. The ...

Drugs associated with bullous pemphigoid: role of ΗΜG-COa reductase inhibitors

Papadopoulou A., Zafiriou E., Koukoulis G.K., Roussaki-Schulze A.V. (2020)

[No abstract available]

Early outcomes of the t-Branch off-the-shelf multi-branched stent graft in 542 patients for elective and urgent aortic pathologies: A retrospective observational study

Kölbel T., Spanos K., Jama K., Behrendt C.-A., Panuccio G., Eleshra A., Rohlffs F., Jakimowicz T. (2021)

Objective: The t-Branch, a standardized off-the-shelf multi-branched stent graft has been used for the treatment of elective and urgent cases in aortic disease. The aim of this study was to assess the early outcomes in ...

The effects of old, new and emerging medicines on metabolic aberrations in PCOS

Bargiota, A.; Diamanti-Kandarakis, E. (2012)

Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age that is associated with significant adverse short- and long-term health consequences. Multiple metabolic aberrations, such as ...

Endograft Specific Haemodynamics After Endovascular Aneurysm Repair: Flow Characteristics of Four Stent Graft Systems

Raptis A., Xenos M., Spanos K., Kouvelos G., Giannoukas A., Matsagkas M. (2019)

Objectives: The implication of haemodynamics in the occurrence of complications after endovascular aneurysm repair (EVAR) has been raised in the literature. Different aortic stent graft configurations may lead to different ...

Epidemiology of Hypertension among Patients on Peritoneal Dialysis Using Standardized Office and Ambulatory Blood Pressure Recordings

Vareta G., Georgianos P.I., Vaios V., Sgouropoulou V., Roumeliotis S., Georgoulidou A., Dounousi E., Eleftheriadis T., Papagianni A., Balaskas E.V., Zebekakis P.E., Liakopoulos V. (2022)

Introduction: Prior studies conducted in peritoneal dialysis (PD) patients in the late 1990s provided considerably variable estimates of the prevalence and control of hypertension. The present study aimed to investigate ...

Expert consensus on the rational clinical use of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors

Achimastos A., Alexandrides T., Alexopoulos D., Athyros V., Bargiota A., Bilianou E., Chrysochoou C., Drogari E., Elisaf M., Ganotakis E., Goudevenos I., Ioannidis I., Kolovou G., Kotsis V., Lekakis I., Liberopoulos E., Melidonis A., Nikolaou V., Ntaios G., Papanas N., Pappas S., Pitsavos C., Rallidis L., Richter D., Skoumas I., Tentolouris N., Tousoulis D., Tselepis A., Tsioufis K., Tziakas D., Tziomalos K., Vardas P., Vlachopoulo C., Vlahakos D. (2016)

Two proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, evolocumab and alirocumab, have recently been approved by both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for the ...