Parcourir par sujet "cardiotoxicity"
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Breast radiotherapy and early adverse cardiac effects. The role of serum biomarkers and strain echocardiography
(2019)Breast cancer radiotherapy has a clear benefit for both long-term survival and local recurrence rate. However, there is still much concern about the early radiation-induced heart toxicity. This article aimed to clarify the ... -
Cardiotoxicity in rabbits after long-term nandrolone decanoate administration
(2016)Abuse of anabolic androgenic steroids is linked to a variety of cardiovascular complications. The aim of our study was to investigate the possible cardiovascular effects of nandrolone decanoate on young rabbits using ... -
Cardiotoxicity of Chemical Substances: An Emerging Hazard Class
(2022)(1) Background: Human health risks and hazards from chemical substances are well regulated internationally. However, cardiotoxicity, is not defined as a stand-alone hazard and therefore there are no defined criteria for ... -
Clozapine associated with autoimmune reaction, fever and low level cardiotoxicity - a case report
(2017)Background: Clozapine is a second-generation antipsychotic drug used in treatment-resistant schizophrenia. Fever induced by clozapine is a rather frequent side-effect which usually occurs in the first 4 weeks of treatment. ... -
Pesticides and cardiotoxicity. Where do we stand?
(2018)Cardiovascular diseases are among the most significant causes of mortality in humans. Pesticides toxicity and risk for human health are controlled at a European level through a well-developed regulatory network, but ... -
The role of TNF-α, Fas/Fas ligand system and NT-proBNP in the early detection of asymptomatic left ventricular dysfunction in cancer patients treated with anthracyclines
(2015)Background: Anthracycline-induced cardiotoxicity typically presents as congestive heart failure (CHF). As immuno-inflammatory activation and apoptosis are important mechanisms in the process of heart failure, the use of ... -
Simulating real-life exposures to uncover possible risks to human health: A proposed consensus for a novel methodological approach
(2017)In real life, consumers are exposed to complex mixtures of chemicals via food, water and commercial products consumption. Since risk assessment usually focuses on individual compounds, the current regulatory approach doesn't ... -
Taxane & cyclophosphamide vs anthracycline & taxane-based chemotherapy as adjuvant treatment for breast cancer: A pooled analysis of randomized controlled trias by the hellenic academy of oncology
(2019)Background: Adjuvant chemotherapy has an indisputable value for early breast cancer patients. Anthracycline and taxane-based regimens (TaxAC) have not been proven superior to taxane & cyclophosphamide (TC), a less toxic ... -
What is considered cardiotoxicity of anthracyclines in animal studies
(2020)Anthracyclines are commonly used anticancer drugs with well.known and extensively studied cardiotoxic effects in humans. In the clinical setting guidelines for assessing cardiotoxicity are well.established with important ...