Parcourir par sujet "adaptive immunity"

Anti-GP2 antibodies in inflammatory bowel disease patients with ileal pouch

Pavlidis, P.; Forbes, A.; Bogdanos, D. P. (2013)

Are psoriasis and psoriatic arthritis the same disease? The IL-23/IL-17 axis data

Sakkas L.I., Bogdanos D.P. (2017)

Psoriatic arthritis (PsA) is a psoriasis (Ps)-associated inflammatory joint disease that affects peripheral joints, entheses, spine, and eyes. PsA and Ps are likely to be the same disease. PsA develops in nearly 70% of ...

The challenges of primary biliary cholangitis: What is new and what needs to be done

Terziroli Beretta-Piccoli B., Mieli-Vergani G., Vergani D., Vierling J.M., Adams D., Alpini G., Banales J.M., Beuers U., Björnsson E., Bowlus C., Carbone M., Chazouillères O., Dalekos G., De Gottardi A., Harada K., Hirschfield G., Invernizzi P., Jones D., Krawitt E., Lanzavecchia A., Lian Z.-X., Ma X., Manns M., Mavilio D., Quigley E.M., Sallusto F., Shimoda S., Strazzabosco M., Swain M., Tanaka A., Trauner M., Tsuneyama K., Zigmond E., Gershwin M.E. (2019)

Primary Biliary Cholangitis (PBC) is an uncommon, chronic, cholangiopathy of autoimmune origin and unknown etiology characterized by positive anti-mitochondrial autoantibodies (AMA), female preponderance and progression ...

Common variable immunodeficiency and asthma: Coexistence or coincidence?

Kotsiou O.S., Gourgoulianis K.I., Daniil Z. (2020)

[No abstract available]

A Critical Appraisal of the Effects of Anesthetics on Immune-system Modulation in Critically Ill Patients With COVID-19

Chalkias A., Barreto E.F., Laou E., Kolonia K., Scheetz M.H., Gourgoulianis K., Pantazopoulos I., Xanthos T. (2021)

Purpose: The aim of the present article was to briefly summarize current knowledge about the immunomodulatory effects of general anesthetics and the possible clinical effects of this immunomodulation in patients with ...

Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection

Xu, H. C.; Huang, J.; Khairnar, V.; Duhan, V.; Pandyra, A. A.; Grusdat, M.; Shinde, P.; McIlwain, D. R.; Maney, S. K.; Gommerman, J.; Löhning, M.; Ohashi, P. S.; Mak, T. W.; Pieper, K.; Sic, H.; Speletas, M.; Eibel, H.; Ware, C. F.; Tumanov, A. V.; Kruglov, A. A.; Nedospasov, S. A.; Häusinger, D.; Recher, M.; Lang, K. S.; Lang, P. A. (2015)

The B cell-activating factor (BAFF) is critical for B cell development and humoral immunity in mice and humans. While the role of BAFF in B cells has been widely described, its role in innate immunity remains unknown. Using ...

The emerging role of helicobacter pylori-induced metabolic gastrointestinal dysmotility and neurodegeneration

Kountouras J., Boziki M., Polyzos S.A., Katsinelos P., Gavalas E., Zeglinas C., Tzivras D., Romiopoulos I., Giorgakis N., Anastasiadou K., Vardaka E., Kountouras C., Kazakos E., Giartza-Taxidou E., Deretzi G., Dardiotis E., Kotronis G., Doulberis M. (2017)

Helicobacter pylori infection (Hp-I) is a prevalent disorder identified in themajority of the population in many countries around the world and is responsible for substantial gastrointestinal morbidity. Likewise, ...

Gene Expression Meta-Analysis of Potential Shared and Unique Pathways between Autoimmune Diseases under Anti-TNFα Therapy

Antonatos C., Panoutsopoulou M., Georgakilas G.K., Evangelou E., Vasilopoulos Y. (2022)

While anti-TNFα has been established as an effective therapeutic approach for several autoimmune diseases, results from clinical trials have uncovered heterogeneous patients’ response to therapy. Here, we conducted a ...

Hepatitis D virus-specific cytokine responses in patients with chronic hepatitis delta before and during interferon alfa-treatment

Grabowski, J.; Yurdaydìn, C.; Zachou, K.; Buggisch, P.; Hofmann, W. P.; Jaroszewicz, J.; Schlaphoff, V.; Manns, M. P.; Cornberg, M.; Wedemeyer, H. (2011)

Background: Hepatitis delta is caused by infection with the hepatitis D virus (HDV) and is considered the most severe form of viral hepatitis. Treatment options for hepatitis delta are limited, with only 25% of patients ...

Highly Dynamic Exon Shuffling in Candidate Pathogen Receptors ... What if Brown Algae Were Capable of Adaptive Immunity?

Zambounis, A.; Elias, M.; Sterck, L.; Maumus, F.; Gachon, C. M. M. (2012)

Pathogen recognition is the first step of immune reactions. In animals and plants, direct or indirect pathogen recognition is often mediated by a wealth of fast-evolving receptors, many of which contain ligand-binding and ...

Identification of the novel HLA-DRB1*11:192 allele by sequence-based typing in Greece

Sarri C.A., Markantoni M., Hadjichristidoulou C., Mamuris Z. (2016)

In Mixed Lymphocyte Reaction, the Hypoxia-Inducible Factor Prolyl-Hydroxylase Inhibitor Roxadustat Suppresses Cellular and Humoral Alloimmunity

Eleftheriadis T., Pissas G., Mavropoulos A., Nikolaou E., Filippidis G., Liakopoulos V., Stefanidis I. (2020)

Hypoxia-inducible factor (HIF) prolyl-hydroxylase inhibitors are currently used for the treatment of renal anemia. Since HIF affects immune cells, we evaluated the effect of such a drug, the roxadustat, on adaptive immunity. ...

Lessons We Have Learned Regarding Seroprevalence in High and Low SARS-CoV-2 Contexts in Greece before the Omicron Pandemic Wave

Kotsiou O.S., Vavougios G.D., Papagiannis D., Matsiatsiou E., Avgeri D., Fradelos E.C., Siachpazidou D.I., Perlepe G., Miziou A., Kyritsis A., Gogou E., Kalampokas S., Kalantzis G., Kotsios V.S., Gourgoulianis K.I. (2022)

Background: Antibody seroprevalence in rural communities remains poorly investigated. We compared the SARS-CoV-2 seroprevalence in two Greek communities in June and July 2021 after the end of the Delta-driven pandemic wave ...