Parcourir par sujet "Virus Diseases"

From microbiome to infectome in autoimmunity

Bogdanos D.P., Sakkas L.I. (2017)

Purpose of review The current review discusses the pros and cons of the microbiome studies conducted in search of the association between microbiota and autoimmunity. Recent findings We focus on the role of infectome and ...

Mycobacterial immunomodulation and viral manipulation of neuronal copper efflux in the setting of sporadic Parkinson's disease: A multi – hit, outside – in hypothesis of its pathogenesis

Vavougios G.D. (2020)

Following Braak's hypothesis on the infectious pathogenesis of sporadic Parkinson's disease (sPD), several bacteria and viruses have been investigated as likely culprits. Recent research has focused on neuroinvasive influenza ...

Neurodegeneration and inflammation—an interesting interplay in parkinson’s disease

Marogianni C., Sokratous M., Dardiotis E., Hadjigeorgiou G.M., Bogdanos D., Xiromerisiou G. (2020)

Parkinson’s disease (PD) is a neurodegenerative disorder, caused by, so far, unknown pathogenetic mechanisms. There is no doubt that pro-inflammatory immune-mediated mechanisms are pivotal to the pathogenicity and progression ...

Overlapping host pathways between SARS-CoV-2 and its potential copathogens: An in silico analysis

Vavougios G.D. (2020)

Background: SARS-CoV-2 coinfection with other viral and bacterial pathogens and their interactions are increasingly recognized in the literature as potential determinants of COVID-19 phenotypes. The aim of this study was ...

Trained immunity in viral infections, Alzheimer's disease and multiple sclerosis: A convergence in type I interferon signalling and IFNβ-1a

Vavougios G.D., Mavridis T., Artemiadis A., Krogfelt K.A., Hadjigeorgiou G. (2022)

Type I interferon (IFN-I) signalling represents a major target for modulation in a virus' bid for latency. IFN-I perturbations are also present in such as Alzheimer's disease (AD) and multiple sclerosis (MS), where viral ...

Viruses and endogenous retroviruses in multiple sclerosis: From correlation to causation

Mentis A.-F.A., Dardiotis E., Grigoriadis N., Petinaki E., Hadjigeorgiou G.M. (2017)

Multiple sclerosis is an immune-mediated disease with an environmental component. According to a long-standing but unproven hypothesis dating to initial descriptions of multiple sclerosis (MS) at the end of the 19th century, ...