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Effects of the active constituents of Crocus sativus L., crocins, in an animal model of anxiety
(2008)Crocus sativus L. is a plant cultivated in various parts of the world. Crocins are among the active components of Crocus sativus L. The present study was designed to investigate in the rat whether or not crocins possess ... -
The metabotropic glutamate 2/3 receptor agonist LY379268 induces anxiety-like behavior at the highest dose tested in two rat models of anxiety
(2013)The activation of Group If metabotropic glutamate 2/3 (mGlu(2/3)) receptors reduces the excessive glutamate release that is hypothesized to be associated with neurodegenerative and psychiatric disorders. LY379268 is a ...