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Accuracy of leptin serum level in diagnosing ventilator-associated pneumonia: a case-control study
(2014)Background. Undernutrition causes a reduction of body-fat mass and a decrease in the circulating concentration of leptin which impairs the production of proinflammatory cytokines and increases the incidence of infectious ... -
Advances in Antibacterial Therapy Against Emerging Bacterial Pathogens
(2009)During the last decade, both gram-positive and gram-negative bacteria that are resistant to most or all available antibacterial classes have become increasingly prevalent nosocomial pathogens, particularly among immunocompromised ... -
Confronting multidrug-resistant Acinetobacter baumannii: a review
(2011)Multidrug-resistant Acinetobacter baumannii (MDR-AB) infections are difficult to treat owing to the extremely limited armamentarium. The present review reports all available treatment options against MDR-AB, including ... -
Diagnostic and prognostic impact of brain natriuretic peptide in cardiac and noncardiac diseases
(2008)OBJECTIVE: Cardiac secretion of brain natriuretic peptide (BNP) increases with the progression of congestive heart failure (CHF). The plasma measurement of BNP emerged recently as a useful, cost-effective biomarker for the ... -
Global evolution of multidrug-resistant Acinetobacter baumannii clonal lineages
(2013)The rapid expansion of Acinetobacter baumannii clinical isolates exhibiting resistance to carbapenems and most or all available antibiotics during the last decade is a worrying evolution. The apparent predominance of a few ... -
Identification of staphylococci by Phoenix: validation of a new protocol and comparison with Vitek 2
(2010)Because of their frequent isolation in the routine laboratory and their increasing clinical significance, fast and accurate species identification of staphylococci may be required, this can only be achieved by automated ... -
Impact of appropriate antimicrobial treatment on transition from ventilator-associated tracheobronchitis to ventilator-associated pneumonia
(2014)Introduction: Two small randomized controlled trials have suggested beneficial effects of antibiotic treatment in patients with ventilator-associated tracheobronchitis (VAT). The primary aim of this study is to determine ... -
Malpractice issues in modern anaesthesiology
(2007)Medical malpractice has been raised as an important problem in daily practice, while the media and public remain unforgiving to those perceived to have harmed the patients' life. This article highlights important legal ... -
New insights into the mechanisms involved in B-type natriuretic peptide elevation and its prognostic value in septic patients
(2014)Introduction: Elevated plasma B-type natriuretic peptide (BNP) levels in patients with critical sepsis (severe sepsis and septic shock) may indicate septic cardiomyopathy. However, multiple heterogeneous conditions may ... -
The role of obesity in the immune response during sepsis
(2014)BACKGROUND/OBJECTIVES: Sepsis is one of the most important causes of mortality in the developed world, where almost two-thirds of the population suffer from obesity. Therefore, the coexistence of both conditions has become ... -
Rotavirus Gastroenteritis in a Neonatal Unit of a Greek Tertiary Hospital: Clinical Characteristics and Genotypes
(2015)Introduction Rotavirus (RV) infection in neonatal age can be mild or even asymptomatic. Several studies have reported that RV is responsible for 31%-87% of pediatric nosocomial diarrhea and causes gastroenteritis outbreaks ... -
Successful control of a neonatal outbreak caused mainly by ST20 multidrug-resistant SHV-5-producing Klebsiella pneumoniae, Greece
(2014)Background: Extended spectrum beta-lactamase-producing Klebsiella pneumoniae (ESBL-Kp) infection can cause significant morbidity and mortality in neonates. We investigated a nosocomial ESBL-Kp outbreak in a neonatal intensive ... -
VENOUS OXYGEN SATURATION AND LACTATE GRADIENT FROM SUPERIOR VENA CAVA TO PULMONARY ARTERY IN PATIENTS WITH SEPTIC SHOCK
(2009)Monitoring of central venous oxygen saturation (S(cv)O(2)) is considered comparable with mixed venous oxygen saturation (S(v)O(2)) in the initial resuscitation phase of septic shock. Our aim was to assess their agreement ... -
Wide dissemination of linezolid-resistant Staphylococcus epidermidis in Greece is associated with a linezolid-dependent ST22 clone
(2015)Objectives: Dependence on linezolid was recently described as significant growth acceleration of linezolid-resistant Staphylococcus epidermidis (LRSE) isolates upon linezolid exposure. We investigated the possible contribution ...