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Parcourir par sujet "E6"

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    • Identification of novel E6-E7 sequence variants of human papillomavirus 16 

      Tsakogiannis, D.; Kyriakopoulou, Z.; Amoutzias, G.; Ruether, I. G. A.; Dimitriou, T. G.; Panotopoulou, E.; Markoulatos, P. (2013)
      The rate of evolution of the human papillomavirus 16 (HPV16) genome is low. However, the ability of the E6 oncoprotein to interact with distinct p53 variants causes selective pressure on the E6 gene. In addition, intratypic ...

    • Prevalence of HPV16 E1-1374 boolean AND 63nt variants in Greek women 

      Tsakogiannis, D.; Kyriakopoulou, Z.; Darmis, F.; Ruether, I. G. A.; Dimitriou, T. G.; Orfanoudakis, G.; Panotopoulou, E.; Markoulatos, P. (2014)
      Recent studies have focused on sequence variation of the HPV16 E1 gene. The present study investigates the prevalence of E1-1374<^>63nt duplication in the Greek population, and the sequence variation at the 5 ' end of the ...