Parcourir par sujet "Crohn's disease"
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Diagnostic value, clinical utility and pathogenic significance of reactivity to the molecular targets of Crohn's disease specific-pancreatic autoantibodies
(2011)Pancreatic autoantibodies (PAB) giving characteristic staining patterns of the exocrine pancreas by indirect immunoflourescence appear to be specific markers of Crohn's disease (CrD), being present in approximarely 30% of ... -
Downregulation of serum epidermal growth factor in patients with inflammatory bowel disease. Is there a link with mucosal damage?
(2010)Background: Epidermal growth factor (EGF) is a multipotent peptide which contributes to epithelial development, inhibition of gastric acid secretion, acceleration of wound healing, and promotion of angiogenesis. The aim ... -
Genetic variants of homocysteine/folate metabolism pathway and risk of inflammatory bowel disease: a synopsis and meta-analysis of genetic association studies
(2010)A synopsis and meta-analysis of studies that investigated the association between genetic variants involved in the homocysteine/folate metabolism pathway and risk of inflammatory bowel disease (IBD) were conducted. Four ... -
Increased serum levels of YKL-40 in patients with inflammatory bowel disease
(2003)Background and aims: Initiation of a fibrotic process has been suggested as part of the intestinal response to chronic inflammation in inflammatory bowel disease. YKL-40 has been proposed as a new serum marker of fibrosis. ... -
Is 99mTc-LeucoScan scintigraphy useful in the assessment of location in Crohn's disease?
(2004)Background/Aims: Scintigraphy with 99mTechnetium HMPAO labelled whitw blood cells (99mTC HMPAO-WBC) is routinely used for the assessment of inflammatory bowel disease (IBD). The main disadvantages of this diagnostic test, ... -
Is there evidence to claim or deny association between variants of the multidrug resistance gene (MDR1 or ABCB1) and inflammatory bowel disease?
(2012)Background: Inflammatory bowel disease (IBD) is a complex disease with a genetic background. Crohn's disease (CD) and ulcerative colitis (UC) are the two main types of IBD. There is indication that variants in the MDR1 ... -
Neutrophil gelatinase-associated lipocalin (NGAL) in inflammatory bowel disease: association with pathophysiology of inflammation, established markers, and disease activity
(2012)Neutrophil gelatinase-associated lipocalin (NGAL) is a multi-potent 25-kDa protein mainly secreted by neutrophils. In inflammatory bowel disease (IBD), overexpression of NGAL in colon epithelium has been previously shown. ...