Parcourir par auteur "Ikonomidis, A."
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Association of biofilm formation and methicillin-resistance with accessory gene regulator (agr) loci in Greek Staphylococcus aureus clones
Ikonomidis, A.; Vasdeki, A.; Kristo, I.; Maniatis, A. N.; Tsakris, A.; Malizos, K. N.; Pournaras, S. (2009)Pathogenicity of Staphylococcus aureus is coordinated by the accessory gene regulator (agr) system. Previous studies suggested that agr Group 11 methicillin-resistant S. aureus (MRSA), a polymorphism that has been associated ... -
Carriage of OXA-58 but not of OXA-51 beta-lactamase gene correlates with carbapenem resistance in Acinetobacter baumannii
Tsakris, A.; Ikonomidis, A.; Pournaras, S.; Spanakis, N.; Markogiannakis, A. (2006) -
Characteristics of Meropenem Heteroresistance in Klebsiella pneumoniae Carbapenemase (KPC)-Producing Clinical Isolates of K-pneumoniae
Pournaras, S.; Kristo, I.; Vrioni, G.; Ikonomidis, A.; Poulou, A.; Petropoulou, D.; Tsakris, A. (2010)Meropenem heteroresistance was investigated in six apparently meropenem-susceptible, Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-KP) clinical isolates, compared with that in carbapenemase-negative, ... -
Characterization of clinical isolates of Pseudomonas aeruginosa heterogeneously resistant to carbapenems
Pournaras, S.; Ikonomidis, A.; Markogiannakis, A.; Spanakis, N.; Maniatis, A. N.; Tsakris, A. (2007)Fourteen apparently carbapenem-susceptible Pseudomonas aeruginosa clinical isolates that exhibited colonies within the inhibition zone around carbapenem discs were analysed. MICs of carbapenems were determined and the ... -
Characterization of In3Mor, a new integron carrying VIM-1 metallo-beta-lactamase and sat1 gene, from Morganella morganii
Tsakris, A.; Ikonomidis, A.; Spanakis, N.; Poulou, A.; Pournaras, S. (2007)Objectives: A carbapenem-resistant Morganella morganii clinical isolate that was phenotypically metallo-beta-lactamase (MBL)-positive was recovered from a Greek patient. The aim of the study was to analyse the structure ... -
Clusters of imipenem-resistant Acinetobacter baumannii clones producing different carbapenemases in an intensive care unit
Tsakris, A.; Ikonomidis, A.; Poulou, A.; Spanakis, N.; Vrizas, D.; Diomidous, M.; Pournaras, S.; Markou, F. (2008)During a 2-year period (April 2005-March 2007), 31 intensive care unit (ICU) patients in a Greek hospital were infected or colonised with imipenem-resistant isolates of Acinetobacter baumannii. Twelve patients died, with ... -
Cross-transmission of multidrug-resistant Acinetobacter baumannii clonal strains causing episodes of sepsis in a trauma intensive care unit
Markogiannakis, A.; Fildisis, G.; Tsiplakou, S.; Ikonomidis, A.; Koutsoukou, A.; Pournaras, S.; Manolis, E. N.; Baltopoulos, G.; Tsakris, A. (2008)OBJECTIVE. To investigate the mode of transmission of imipenem-resistant Acinetobacter baumannii strains causing episodes of sepsis. SETTING. A 7-bed trauma intensive care unit (ICU) in an orthopedic hospital in Greece. ... -
CTX-M enzymes are the most common extended-spectrum beta-lactamases among Escherichia coli in a tertiary Greek hospital
Pournaras, S.; Ikonomidis, A.; Kristo, L.; Tsakris, A.; Maniatis, A. N. (2004) -
CTX-M-type β-lactamases affect community Escherichia coli treatment, Greece [1]
Pournaras, S.; Ikonomidis, A.; Sofianou, D.; Tsakris, A.; Maniatis, A. N. (2004) -
Detection of a novel variant bla(CTX-M-3) extended spectrum beta-lactamase gene in a community-acquired Escherichia coli isolate
Pournaras, S.; Tsakris, A.; Ikonomidis, A.; Markogiannakis, A.; Kristo, I.; Maniatis, A. N. (2006)A highly cefotaxime- and cefepime-resistant but ceftazidime-sensitive Escherichia coli isolate was recovered from a community-acquired urinary infection of a Greek patient. Susceptibility testing, transfer assays, plasmid ... -
Detection of mutations in the FemXAB protein family in oxacillin-susceptible mecA-positive Staphylococcus aureus clinical isolates
Giannouli, S.; Labrou, M.; Kyritsis, A.; Ikonomidis, A.; Pournaras, S.; Stathopoulos, C.; Tsakris, A. (2010)Methicillin-resistant Staphylococcus aureus (MRSA) strains that express the mecA gene but are oxacillin susceptible (OS-MRSA; oxacillin MIC < 2 mg/L) are increasingly reported. To gain molecular and functional insights on ... -
Discordance of meropenem versus imipenem activity against Acinetobacter baumannii
Ikonomidis, A.; Pournaras, S.; Maniatis, A. N.; Legakis, N. J.; Tsakris, A. (2006) -
Efflux system overexpression and decreased OprD contribute to the carbapenem heterogeneity in Pseudomonas aeruginosa
Ikonomidis, A.; Tsakris, A.; Kantzanou, M.; Spanakis, N.; Maniatis, A. N.; Pournaras, S. (2008)Pseudomonas aeruginosa strains exhibiting a heterogeneous mode of growth against carbapenems have been described recently. This study investigated the underlying molecular mechanisms in four genetically unrelated P. ... -
Emergence of carbapenem-resistant enterobacter cloacae carrying VIM-4 metallo-beta-lactamase and SHV-2a extended-spectrum beta-lactamase in a conjugative plasmid
Ikonomidis, A.; Spanakis, N.; Poulou, A.; Pournaras, S.; Markou, F.; Tsakris, A. (2007)Enterobacter cloacae strains are still infrequently resistant to carbapenems. A carbapenem-resistant clinical isolate of E. cloacae producing a plasmid-mediated metallo-beta-lactamase (MBL), VIM-4, was recovered from a ... -
Evaluation of Boronic Acid Disk Tests for Differentiating KPC-Possessing Klebsiella pneumoniae Isolates in the Clinical Laboratory
Tsakris, A.; Kristo, I.; Poulou, A.; Themeli-Digalaki, K.; Ikonomidis, A.; Petropoulou, D.; Pournaras, S.; Sofianou, D. (2009)The worldwide increase in the occurrence and dissemination of KPC beta-lactamases among gram-negative pathogens makes critical the early detection of these enzymes. Boronic acid disk tests using different antibiotic ... -
First occurrence of KPC-2-possessing Klebsiella pneumoniae in a Greek hospital and recommendation for detection with boronic acid disc tests
Tsakris, A.; Kristo, I.; Poulou, A.; Markou, F.; Ikonomidis, A.; Pournaras, S. (2008)To investigate the first KPC carbapenemase-producing Klebsiella pneumoniae isolate from a Greek hospital, including phenotypic methods to aid recognition of this resistance type. A carbapenem-resistant clinical isolate of ... -
Heteroresistance to carbapenems in Acinetobacter baumannii
Pournaras, S.; Ikonomidis, A.; Markogiannakis, A.; Maniatis, A. N.; Tsakris, A. (2005) -
Heteroresistance to Meropenem in Carbapenem-Susceptible Acinetobacter baumannii
Ikonomidis, A.; Neou, E.; Gogou, V.; Vrioni, G.; Tsakris, A.; Pournaras, S. (2009)The characteristics of carbapenem heteroresistance were studied in 14 apparently carbapenem-susceptible Acinetobacter baumannii isolates. The MICs for carbapenems were determined, and the isolates were genotyped by ... -
A highly carbapenem-resistant Pseudomonas aeruginosa isolate with a novel bla(VIM-4)/bla(P1b) integron overexpresses two efflux pumps and lacks OprD
Maniati, M.; Ikonomidis, A.; Mantzana, P.; Daponte, A.; Maniatis, A. N.; Pournaras, S. (2007)Objectives: A Pseudomonas aeruginosa clinical isolate that exhibited high-level carbapenem resistance and produced metallo-beta-lactamase (MBL) was recovered from a Greek patient. This study was conducted to determine the ... -
Identification of a novel bla(OXA-51) variant, bla(OXA-92), from a clinical isolate of Acinetobacter baumannii
Tsakris, A.; Ikonomidis, A.; Spanakis, N.; Pournaras, S.; Bethimouti, K. (2007)