Parcourir par auteur "Craig, S. N."
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Iterative Conversion of Cyclin Binding Groove Peptides into Drug like CDK Inhibitors with Antitumor Activity
Premnath, P. N.; Craig, S. N.; Liu, S.; Anderson, E. L.; Grigoroudis, A. I.; Kontopidis, G.; Perkins, T. L.; Wyatt, M. D.; Pittman, D. L.; McInnes, C. (2015)The cyclin groove is an important recognition site for substrates of the cell cycle cyclin dependent kinases and provides an opportunity for highly selective inhibition of kinase activity through a non-ATP competitive ...