Listar por tema "molsidomine"
Mostrando ítems 1-9 de 9
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The 5-HT1A receptor and recognition memory possible modulation of its behavioral effects by the nitrergic system
(2005)Functional activation of the 5-HT1A receptor inhibits cognition, although discrepant findings have also been reported. The present study was designed to investigate the role of the 5-HT1A receptor on recognition memory in ... -
Effects of low doses of different nitric oxide (NO) donors in rat models of obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD)
(2022)Several lines of evidence suggest that the intra- and inter-cellular messenger nitric oxide (NO) is critically involved in anxiety. Contrasting findings are reported, however, regarding the effects of NO donors in preclinical ... -
The GABA(B) receptor and recognition memory: Possible modulation if its behavioral effects by the nitrergic system
(2003)Functional activation of the GABA(B) receptor inhibits learning and memory processes, though discrepant findings, in this context, have also been reported. The present study was designed to investigate the role of the ... -
Memantine and recognition memory: Possible facilitation of its behavioral effects by the nitric oxide (NO) donor molsidomine
(2007)The effects of the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist memantine on recognition memory were investigated in the rat by using the object recognition task. In addition, a possible interaction ... -
Molsidomine antagonizes L-NAME-induced acquisition deficits in a recognition memory task in the rat
(2003)The present study was designed to investigate the role of nitric oxide (NO) on the acquisition of a recognition memory, task in the rat. For this purpose, the effects on memory exerted by pre-training administration of the ... -
The nitric oxide donor molsidomine antagonizes age-related memory deficits in the rat
(2005)The effects of the nitric oxide (NO) donor molsidomine on aged rats' cognition were evaluated in two different behavioral tasks: the step-through passive avoidance paradigm and the object recognition test. Post-training ... -
The nitric oxide donor molsidomine induces anxiolytic-like behaviour in two different rat models of anxiety
(2015)Experimental evidence indicates the implication of the nitric oxide (NO) in anxiety. Contradictory results were reported however, concerning the effects of NO donors in animal models of anxiety disorders. The present study ... -
The role of nitric oxide donors in schizophrenia: Basic studies and clinical applications
(2015)Schizophrenia is a complex and chronic mental health disease that affects nearly 1% of the population worldwide. While the current antipsychotic medications have profoundly impacted the treatment of schizophrenia over the ...