Listar por tema "metabolite"

Altered activity of xenobiotic detoxifying enzymes at menopause – A cross-sectional study

Tsiokou V., Kilindris T., Begas E., Kouvaras E., Kouretas D., Asprodini E.K. (2020)

Xenobiotic metabolism at menopause is an under-investigated topic, albeit women spend one-third of their life in the postmenopausal period. The present study examined the effect of menopause on the in vivo activities of ...

Biostimulants application: A low input cropping management tool for sustainable farming of vegetables

Shahrajabian M.H., Chaski C., Polyzos N., Petropoulos S.A. (2021)

Biostimulants, are a diverse class of compounds including substances or microorganism which have positive impacts on plant growth, yield and chemical composition as well as boosting effects to biotic and abiotic stress ...

Blame it on the metabolite: 3,5-dichloroaniline rather than the parent compound is responsible for the decreasing diversity and function of soil microorganisms

Vasileiadis S., Puglisi E., Papadopoulou E.S., Pertile G., Suciu N., Pappolla R.A., Tourna M., Karas P.A., Papadimitriou F., Kasiotakis A., Ipsilanti N., Ferrarini A., Sulowicz S., Fornasier F., Menkissoglu-Spiroudi U., Nicol G.W., Trevisan M., Karpouzas D.G. (2018)

Pesticides are key stressors of soil microorganisms with reciprocal effects on ecosystem functioning. These effects have been mainly attributed to the parent compounds, while the impact of their transformation products ...

Comparison of Novel and Established Nitrification Inhibitors Relevant to Agriculture on Soil Ammonia- and Nitrite-Oxidizing Isolates

Papadopoulou E.S., Bachtsevani E., Lampronikou E., Adamou E., Katsaouni A., Vasileiadis S., Thion C., Menkissoglu-Spiroudi U., Nicol G.W., Karpouzas D.G. (2020)

Nitrification inhibitors (NIs) applied to soil reduce nitrogen fertilizer losses from agro-ecosystems. NIs that are currently registered for use in agriculture appear to selectively inhibit ammonia-oxidizing bacteria (AOB), ...

Isolation and characterization of bacteria from acidic pristine soil environment able to transform iprodione and 3,5-dichloraniline

Campos, M.; Perruchon, C.; Vasilieiadis, S.; Menkissoglu-Spiroudi, U.; Karpouzas, D. G.; Diez, M. C. (2015)

Iprodione is a fungicide commonly used in a range of crops resulting in its common detection in natural water resources. Biological degradation constitutes the major dissipation processes controlling its environmental ...

Land spreading of wastewaters from the fruit-packaging industry and potential effects on soil microbes: Effects of the antioxidant ethoxyquin and its metabolites on ammonia oxidizers

Papadopoulou E.S., Tsachidou B., Sulowicz S., Menkissoglu-Spiroudi U., Karpouzas D.G. (2016)

Thiabendazole (TBZ), imazalil (IMZ), ortho-phenylphenol (OPP), diphenylamine (DPA), and ethoxyquin (EQ) are used in fruitpackaging plants (FPP) with the stipulation that wastewaters produced by their application would be ...

Novel insights into the metabolic pathway of iprodione by soil bacteria

Campos M., Karas P.S., Perruchon C., Papadopoulou E.S., Christou V., Menkissoglou-Spiroudi U., Diez M.C., Karpouzas D.G. (2017)

Microbial degradation constitutes the key soil dissipation process for iprodione. We recently isolated a consortium, composed of an Arthrobacter sp. strain C1 and an Achromobacter sp. strain C2, that was able to convert ...

The pivotal role of protein phosphorylation in the control of yeast central metabolism

Vlastaridis P., Papakyriakou A., Chaliotis A., Stratikos E., Oliver S.G., Amoutzias G.D. (2017)

Protein phosphorylation is the most frequent eukaryotic post-translational modification and can act as either a molecular switch or rheostat for protein functions. The deliberate manipulation of protein phosphorylation has ...

The Serum and Fecal Metabolomic Profiles of Growing Kittens Treated with Amoxicillin/Clavulanic Acid or Doxycycline

Stavroulaki E.M., Suchodolski J.S., Pilla R., Fosgate G.T., Sung C.-H., Lidbury J., Steiner J.M., Xenoulis P.G. (2022)

The long-term impact of antibiotics on the serum and fecal metabolome of kittens has not yet been investigated. Therefore, the objective of this study was to evaluate the serum and fecal metabolome of kittens with an upper ...

Targeted and global pharmacometabolomics in everolimus-based immunosuppression: association of co-medication and lysophosphatidylcholines with dose requirement

Lesche D., Sigurdardottir V., Leichtle A.B., Nakas C.T., Christians U., Englberger L., Fiedler M., Largiadèr C.R., Mohacsi P., Sistonen J. (2018)

Introduction: The immunosuppressive therapy with everolimus (ERL) after heart transplantation is characterized by a narrow therapeutic window and a substantial variability in dose requirement. Factors explaining this ...

Unraveling the roles of plant specialized metabolites: using synthetic biology to design molecular biosensors

Garagounis C., Delkis N., Papadopoulou K.K. (2021)

Plants are a rich source of specialized metabolites with a broad range of bioactivities and many applications in human daily life. Over the past decades significant progress has been made in identifying many such metabolites ...

Urinary Metabolomics From a Dose-Fractionated Polymyxin B Rat Model of Acute Kidney Injury

Locci E., Liu J., Pais G.M., Chighine A., Kahnamoei D.A., Xanthos T., Chalkias A., Lee A., Hauser A.R., Chang J., Rhodes N.J., d'Aloja E., Scheetz M.H. (2022)

Background: Polymyxin B treatment is limited by kidney injury. This study sought to identify Polymyxin B-related urinary metabolomic profile modifications for early detection of polymyxin-associated nephrotoxicity. Methods: ...