Listar por tema "memory"

The 5-HT1A receptor and recognition memory possible modulation of its behavioral effects by the nitrergic system

Pitsikas, N.; Tsitsirigou, S.; Zisopoulou, S.; Sakellaridis, N. (2005)

Functional activation of the 5-HT1A receptor inhibits cognition, although discrepant findings have also been reported. The present study was designed to investigate the role of the 5-HT1A receptor on recognition memory in ...

Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study

Lipnicki D.M., Crawford J.D., Dutta R., Thalamuthu A., Kochan N.A., Andrews G., Lima-Costa M.F., Castro-Costa E., Brayne C., Matthews F.E., Stephan B.C.M., Lipton R.B., Katz M.J., Ritchie K., Scali J., Ancelin M.-L., Scarmeas N., Yannakoulia M., Dardiotis E., Lam L.C.W., Wong C.H.Y., Fung A.W.T., Guaita A., Vaccaro R., Davin A., Kim K.W., Han J.W., Kim T.H., Anstey K.J., Cherbuin N., Butterworth P., Scazufca M., Kumagai S., Chen S., Narazaki K., Ng T.P., Gao Q., Reppermund S., Brodaty H., Lobo A., Lopez-Anton R., Santabárbara J., Sachdev P.S., Cohort Studies of Memory in an International Consortium (COSMIC) (2017)

Background: The prevalence of dementia varies around the world, potentially contributed to by international differences in rates of age-related cognitive decline. Our primary goal was to investigate how rates of age-related ...

Antihypertensive Medication Class and the Risk of Dementia and Cognitive Decline in Older Adults: A Secondary Analysis of the Prospective HELIAD Cohort

Liampas I., Hatzimanolis A., Siokas V., Yannakoulia M., Kosmidis M.H., Sakka P., Hadjigeorgiou G.M., Scarmeas N., Dardiotis E. (2022)

Background: It is unclear whether the main antihypertensive medication classes (diuretics, calcium channel blockers, beta-blockers, angiotensin converting enzyme inhibitors, and angiotensin receptor blockers (ARBs)) are ...

Assessing functional status using the IADL-extended scale: Results from the HELIAD study

Kalligerou F., Fieo R., Paraskevas G.P., Zalonis I., Kosmidis M.H., Yannakoulia M., Ntanasi E., Dardiotis E., Hadjigeorgiou G., Sakka P., Scarmeas N. (2020)

Objectives: Instrumental activities of daily living (IADL) have been operationalized as exhibiting a greater level of complexity than basic ADL. In the same way, incorporating more advanced ADLs may increase the sensitivity ...

Association between 9p21–23 Locus and Frailty in a Community-Dwelling Greek Population: Results from the Hellenic Longitudinal Investigation of Ageing and Diet

Mourtzi N., Hatzimanolis A., Xiromerisiou G., Ntanasi E., Georgakis M.K., Ramirez A., Heilmann-Heimbach S., Grenier-Boley B., Lambert J.C., Yannakoulia M., Kosmidis M., Dardiotis E., Hadjigeorgiou G., Sakka P., Scarmeas N. (2022)

Background: Frailty is a complex geriatric syndrome arising from a combination of genetic and environmental factors and is associated with adverse health outcomes and mortality. A recent study reported an association between ...

Can a Virtual Reality Cognitive Training Application Fulfill a Dual Role? Using the Virtual Supermarket Cognitive Training Application as a Screening Tool for Mild Cognitive Impairment

Zygouris, S.; Giakoumis, D.; Votis, K.; Doumpoulakis, S.; Ntovas, K.; Segkouli, S.; Karagiannidis, C.; Tzovaras, D.; Tsolaki, M. (2015)

Background: Recent research advocates the potential of virtual reality (VR) applications in assessing cognitive functions highlighting the possibility of using a VR application for mild cognitive impairment (MCI) screening. ...

Cognitive function and exercise training for chronic renal disease patients: A literature review

Kaltsatou, A.; Grigoriou, S. S.; Karatzaferi, C.; Giannaki, C. D.; Stefanidis, I.; Sakkas, G. K. (2015)

Objective: Cognitive impairment is very often noted in patients with Chronic Kidney Disease (CKD). Even though, exercise is considered to be a quantifiable activity that improves cognition in animals and humans, it seems ...

Cognitive impairment in heart failure

Dardiotis, E.; Giamouzis, G.; Mastrogiannis, D.; Vogiatzi, C.; Skoularigis, J.; Triposkiadis, F.; Hadjigeorgiou, G. M. (2012)

Cognitive impairment (CI) is increasingly recognized as a common adverse consequence of heart failure (HF). Although the exact mechanisms remain unclear, microembolism, chronic or intermittent cerebral hypoperfusion, and/or ...

Computerized cognitive rehabilitation for treatment of cognitive impairment in multiple sclerosis: An explorative study

Vilou I., Bakirtzis C., Artemiadis A., Ioannidis P., Papadimitriou M., Konstantinopoulou E., Aretouli E., Messinis L., Nasios G., Dardiotis E., Kosmidis M.H., Grigoriadis N. (2020)

In this explorative study, forty-seven patients with relapsing-remitting multiple sclerosis were randomized to a custom 6-week cognitive rehabilitation intervention (n = 23) using the BrainHQTM web-based platform and to a ...

Conventional cardiovascular risk factors in Transient Global Amnesia: Systematic review and proposition of a novel hypothesis

Liampas I., Raptopoulou M., Siokas V., Bakirtzis C., Tsouris Z., Aloizou A.-M., Dastamani M., Brotis A., Bogdanos D., Dardiotis E. (2021)

Transient Global Amnesia (TGA) is an enigmatic amnestic syndrome. We conducted a systematic review to investigate the relationship between the conventional cardiovascular risk factors and TGA. MEDLINE, CENTRAL, EMBASE and ...

Crocins, the bioactive components of crocus sativus l., counteract the disrupting effects of anesthetic ketamine on memory in rats

Pitsikas N., Tarantilis P.A. (2021)

Consistent experimental evidence suggests that anesthetic doses of the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist ketamine cause severe memory impairments in rodents. Crocins are among the various ...

Dementia incidence in the elderly population of greece: Results from the HELIAD study

Vlachos G.S., Kosmidis M.H., Yannakoulia M., Dardiotis E., Hadjigeorgiou G., Tzoulaki I., Georgiou A.N., Sakka P., Anastasiou C.A., Stefanis L., Scarmeas N. (2021)

Objectives:Recently a declining trend in dementia incidence rates has been reported in high-income countries. We investigated dementia incidence in a representative sample of the Greek population in the age group of 65 ...

Effects of the active constituents of Crocus sativus L. crocins and their combination with memantine on recognition memory in rats

Pitsikas N., Tarantilis P.A. (2018)

Crocus sativus L., is a plant cultivated in many countries of the world. Crocins are among the active constituents of C. sativus and their implication in cognition has been proposed. The present study was designed to ...

Efficacy of computer-based cognitive training in neuropsychological performance of patients with multiple sclerosis: A systematic review and meta-analysis

Dardiotis E., Nousia A., Siokas V., Tsouris Z., Andravizou A., Mentis A.-F.A., Florou D., Messinis L., Nasios G. (2018)

Importance Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system characterized by relapses and a progressive course that may lead to accumulation of physical and cognitive disability. ...

Evaluation of memory performance in patients with brain disorders following rTMS treatment. A systematic review

Bonotis K., Anargyros K., Liaskopoulos N., Barlogianni A.-M. (2022)

Objective: Repetitive transcranial magnetic stimulation (rTMS) is being used as a non-invasive, non-pharmacological treatment with emerging clinical applications. The objective of this systematic review is to assess the ...

Flumazenil but not bicuculline counteract the impairing effects of anesthetic ketamine on recognition memory in rats. Evidence for a functional interaction between the GABA A -benzodiazepine receptor and ketamine?

Lafioniatis A., Bermperian V.C., Pitsikas N. (2019)

Experimental evidence indicates that anesthetic doses of the non-competitive NMDA receptor antagonist ketamine impair memory abilities in rodents. The mechanism by which anesthetic ketamine produces its adverse behavioural ...

Higher probability of prodromal Parkinson disease is related to lower cognitive performance

Bougea A., Maraki M.I., Yannakoulia M., Stamelou M., Xiromerisiou G., Kosmidis M.H., Ntanasi E., Dardiotis E., Hadjigeorgiou G.M., Sakka P., Anastasiou C.A., Stefanis L., Scarmeas N. (2019)

ObjectiveGiven the limited information on cognitive function before Parkinson disease (PD) clinical onset in the general population, we sought to assess prodromal PD (pPD) probability and relate it to detailed cognitive ...

Identifying Appropriate Neuropsychological Tests for Uneducated/Illiterate Older Individuals

Mandyla M.-A., Yannakoulia M., Hadjigeorgiou G., Dardiotis E., Scarmeas N., Kosmidis M.H. (2021)

Objectives: We investigated the utility of traditional neuropsychological tests in older uneducated/illiterate individuals without dementia to determine the possibility that they are likely not appropriate for this group. ...

Ketamine disrupted storage but not retrieval of information in male rats and apomorphine counteracted its impairing effect

Pitsikas N., Carli M. (2020)

Ketamine, a non-competitive NMDA receptor antagonist, has been reported to mimic the cognitive symptoms of schizophrenia in animals. It has been reported to produce learning and memory deficits in rodents. However, there ...

Mediterranean diet and cognitive health: Initial results from the Hellenic Longitudinal Investigation of Ageing and Diet

Anastasiou C.A., Yannakoulia M., Kosmidis M.H., Dardiotis E., Hadjigeorgiou G.M., Sakka P., Arampatzi X., Bougea A., Labropoulos I., Scarmeas N. (2017)

Background: The Mediterranean dietary pattern has been associated with a decreased risk of many degenerative diseases and cognitive function in particular; however, relevant information from Mediterranean regions, where ...