Listar por tema "cell cycle arrest"
Mostrando ítems 1-4 de 4
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The labdane diterpene sclareol (labd-14-ene-8, 13-diol) induces apoptosis in human tumor cell lines and suppression of tumor growth in vivo via a p53-independent mechanism of action
(2011)The labdane diterpene sclareol has demonstrated significant cytotoxicity against human tumor cell lines and human colon cancer xenografts. Therefore, there is need to elucidate the mode of action of this compound as very ... -
Oxidative Stress and Acute Kidney Injury in Critical Illness: Pathophysiologic Mechanisms - Biomarkers - Interventions, and Future Perspectives
(2017)Acute kidney injury (AKI) is a multifactorial entity that occurs in a variety of clinical settings. Although AKI is not a usual reason for intensive care unit (ICU) admission, it often complicates critically ill patients' ... -
Quercetin accumulates in nuclear structures and triggers specific gene expression in epithelial cells
(2012)Quercetin is a flavonol modifying a number of cell processes in different cell lines. Here, we present evidence that nonconjugated quercetin enters cells possibly via organic anion transporter polypeptides and quickly ... -
Vegetable organosulfur compounds and their health promoting effects
(2017)Background: Trends in modern pharmaceutical science show an increase in demand for new drugs and diet supplements derived from natural products, while during the last decades, great research is conducted regarding the ...