Listar por tema "Solubility"
Mostrando ítems 1-5 de 5
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Aqueous Solubility Enhancement for Bioassays of Insoluble Inhibitors and QSPR Analysis: A TNF-α Study
(2018)The aim of this study is to improve the aqueous solubility of a group of compounds without interfering with their bioassay as well as to create a relevant prediction model. A series of 55 potential small-molecule inhibitors ... -
A comparison of statistical approaches used for the optimization of soluble protein expression in Escherichia coli
(2016)During a discovery project of potential inhibitors for three proteins, TNF-α, RANKL and HO-1, implicated in the pathogenesis of rheumatoid arthritis, significant amounts of purified proteins were required. The application ... -
In vitro and in vivo assessment of vitamin A encapsulation in a liposome–protein delivery system
(2019)Vitamin A (VA) is an essential nutrient needed in small amounts by humans and supports a wide range of biological actions. Retinol, the most common and most biologically active form of VA has also been found to inhibit ... -
Input on the Measurement and Comprehension of CO2 Solubility in Molten Alkali Carbonates in View of Its Valorization
(2020)As the capture and valorization of CO2 in molten carbonates is nowadays becoming a strategic energy topic, the need of accurate solubility measurements of such molecule is becoming compulsory. This study provides a new set ... -
Soluble Urokinase Plasminogen Activator Receptor: A Biomarker for Predicting Complications and Critical Care Admission of COVID-19 Patients
(2020)The novel coronavirus infection has spread worldwide, causing a wide spectrum of clinical manifestations. Most patients develop moderate clinical illness, but a substantial number will experience severe pneumonia, which ...