Listar por tema "RNA Interference"
Mostrando ítems 1-7 de 7
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DIANA-LncBase v3: Indexing experimentally supported miRNA targets on non-coding transcripts
(2020)DIANA-LncBase v3.0 (www.microrna.gr/LncBase) is a reference repository with experimentally supported miRNA targets on non-coding transcripts. Its third version provides approximately half a million entries, corresponding ... -
Enhanced expression of miR-21 and miR-150 is a feature of anti-mitochondrial antibody-negative primary biliary cholangitis
(2020)Background & Aims: Anti-mitochondrial-autoantibodies (AMA) remain a hallmark of Primary Biliary Cholangitis (PBC) however approximately 10% of patients test negative for these antibodies. They do not differ in terms of ... -
Enhancer of rudimentary homologue interacts with scaffold attachment factor B at the nuclear matrix to regulate SR protein phosphorylation
(2017)Scaffold attachment factor B1 (SAFB1) is an integral component of the nuclear matrix of vertebrate cells. It binds to DNA on scaffold/matrix attachment region elements, as well as to RNA and a multitude of different proteins, ... -
Genetically modified organism-free RNA interference: Exogenous application of RNA molecules in plants1[open]
(2020)Since its discovery more than 20 years ago, RNA interference (RNAi) has been extensively used in crop protection platforms. So far, RNAi approaches have been conventionally based on the use of transgenic plants expressing ... -
Lotus SHAGGY-like kinase 1 is required to suppress nodulation in Lotus japonicus
(2019)Glycogen synthase kinase/SHAGGY-like kinases (SKs) are a highly conserved family of signaling proteins that participate in many developmental, cell-differentiation, and metabolic signaling pathways in plants and animals. ... -
Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests
(2019)In insects, rapidly evolving primary sex-determining signals are transduced by a conserved regulatory module controlling sexual differentiation. In the agricultural pest Ceratitis capitata (Mediterranean fruit fly, or ... -
mTORC2 deploys the mRNA binding protein IGF2BP1 to regulate c-MYC expression and promote cell survival
(2021)mTORC2 promotes cell survival by phosphorylating AKT and enhancing its activity. Inactivation of mTORC2 reduces viability through down-regulation of E2F1 caused by up-regulation of c-MYC. An additional target of mTORC2 is ...