Listar por tema "OBSTRUCTIVE PULMONARY-DISEASE"
Mostrando ítems 1-20 de 28
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Acute and Short-term Effects of Secondhand Smoke on Lung Function and Cytokine Production
(2009)Rationale: The acute effect of secondhand smoke (SHS) on lung function and the duration of system disruption remain unknown. Objectives: To assess the SHS effects and their duration on lung function and inflammatory markers. ... -
Adrenomedullin optimises mortality prediction in COPD patients
(2015)Background: Current multicomponent scores that predict mortality in COPD patients might underestimate the systemic component of COPD. Therefore, we evaluated the accuracy of circulating levels of proadrenomedullin (MR-proADM) ... -
Adrenomedullin refines mortality prediction by the BODE index in COPD: the "BODE-A" index
(2014)The BODE (body mass index, airflow obstruction, dyspnoea, exercise capacity) index is well-validated for mortality prediction in chronic obstructive pulmonary disease (COPD). Concentrations of plasma pro-adrenomedullin, a ... -
The Association of Metabolic Syndrome with Adipose Tissue Hormones and Insulin Resistance in Patients with COPD without Co-morbidities
(2011)Chronic obstructive pulmonary disease (COPD) and metabolic syndrome represent common causes of morbidity and mortality in ageing populations. The effect of the co-existence of COPD and metabolic syndrome on adipose tissue ... -
Associations between BODE Index and Systemic Inflammatory Biomarkers in COPD
(2011)Background: COPD is a multicomponent disease and systemic inflammation represents one of the possible mechanisms responsible for its systemic manifestations, including skeletal muscle weakness and cachexia. Fat-free mass ... -
Biomarkers Obtained by Non-Invasive Methods in Patients with COPD: Where do we Stand, what do we Expect?
(2009)Recently, there has been widespread interest in the use of non-invasive methods for the assessment of airway inflammation in a variety of lung diseases including chronic obstructive pulmonary disease ( COPD). Sputum induction ... -
Body Composition in Severe Refractory Asthma: Comparison with COPD Patients and Healthy Smokers
(2010)Background: Body composition is an important parameter for patients with chronic obstructive pulmonary disease (COPD) whereas the association between asthma and obesity is not fully understood. The impact of severe refractory ... -
Characteristics of prevalent and new COPD cases in Greece: the GOLDEN study
(2015)Background: Greece has one of the highest rates of smoking and chronic obstructive pulmonary disease (COPD) in Europe. Aim: The study aimed to record both the disease characteristics among a sample of Greek COPD patients ... -
Chronic bronchitis in rural and industrial areas
(2000)The purpose of the study was the determination of prevalence of chronic bronchitis in people older than 55 years in rural and industrial areas. 569 people over 55 years old living in central Greece were studied. A protocol ... -
Clinical, functional and biochemical changes during recovery from COPD exacerbations
(2009)The pathways underlying chronic obstructive pulmonary disease exacerbations (ECOPD) remain unclear. This study describes the clinical., functional and biochemical changes during recovery from ECOPD. Thirty hospitalized ... -
Comparison of a network of primary care physicians and an open spirometry programme for COPD diagnosis
(2011)Background: Early diagnosis of Chronic Obstructive Pulmonary Disease (COPD) remains the cornerstone for effective management. In this study we compared an open spirometry programme and a case-finding programme providing ... -
Exertional Hypoxemia in Stable COPD Is Common and Predicted by Circulating Proadrenomedullin
(2014)BACKGROUND: The prevalence of exertional hypoxemia in unselected patients with COPD is unknown. Intermittent hypoxia leads to adrenomedullin (ADM) upregulation through the hypoxia-inducible factor-1 pathway. We aimed to ... -
Exhaled breath condensate pH as a biomarker of COPD severity in ex-smokers
(2011)Endogenous airway acidification, as assessed by exhaled breath condensate (EBC) pH, is present in patients with stable COPD. The aim of this study was to measure EBC pH levels in a large cohort of COPD patients and to ... -
Fetuin-A is Associated with Disease Severity and Exacerbation Frequency in Patients with COPD
(2013)Fetuin-A is a liver protein that may serve as an inhibitor of systemic inflammation in humans. In the present study we assessed the levels of fetuin-A in COPD patients in stable condition and on exacerbation in an attempt ... -
Global assessment of the COPD patient: Time to look beyond FEV1?
(2009)COPD is a diverse disease entity with multiple dimensions that uniquely define the patient's performance, morbidity and mortality. FEV1 is both the traditional metric used to define the progression of COPD as well as the ... -
Immediate and short-term consequences of secondhand smoke exposure on the respiratory system
(2011)Purpose of review This review critically evaluates the existing biological evidence regarding the immediate and short-term respiratory consequences of secondhand smoke (SHS). Recent findings A 1-h exposure to SHS at ... -
Impact of dietary shift to higher-antioxidant foods in COPD: a randomised trial
(2010)Chronic obstructive pulmonary disease (COPD) is characterised by increased oxidative stress. Dietary factors, such as ample consumption of foods rich in antioxidants, such as fruit and vegetables, might have beneficial ... -
Isocapnic Cold Air Challenge in Patients with COPD: Are There any Predisposing Factors?
(2008)Cold air hyperventilation is an indirect challenge (cold air challenge, CACh) with high specificity and low sensitivity in defining asthmatic subjects. A small proportion of chronic obstructive pulmonary disease (COPD) ... -
Matrix Metalloproteinases in Respiratory Diseases: From Pathogenesis to Potential Clinical Implications
(2009)Matrix metalloproteinases (MMPs) are zinc-endopeptidases responsible for degradation of the extracellular matrix (ECM) components including basement membrane collagen, interstitial collagen, fibronectin, and various ...