Listar por tema "Frontiers Media S. A"
Mostrando ítems 1-3 de 3
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An easy microwave-assisted synthesis of C8-alkynyl adenine pyranonucleosides as novel cytotoxic antitumor agents
(2015)We describe the synthesis of C8-alkynyl adenine pyranonucleosides 4, 5, and 8-phenylethynyl-adenine (II), via Sonogashira cross-coupling reaction under microwave irradiation. Compounds 4e and II were less cytostatic than ... -
Quantum chemical calculations predict biological function: The case of T cell receptor interaction with a peptide/MHC class I
(2015)A combination of atomic correlation statistics and quantum chemical calculations are shown to predict biological function. In the present study, various antigenic peptide-Major Histocompatibility Complex (pMHC) ligands ... -
Seasonality of post-capture longevity in a medically-important mosquito (Culex pipiens)
(2016)The epidemiological importance of the age structure and longevity potential of wild populations of mosquito disease vectors has been known for over 60 years. However, no routine method currently exists that provides reliable ...