Listar por tema "CK1 delta"

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CK1 delta affects cancer cell adaptation to hypoxia by controlling HIF-1 alpha/ARNT complex formation

Kourti, M.; Mylonis, I.; Giakoumakis, N. N.; Ikonomou, G.; Landegren, U.; Lygerou, Z.; Simos, G. (2014)
CK1 delta restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1 alpha/ARNT complex formation

Kourti, M.; Ikonomou, G.; Giakoumakis, N. N.; Rapsomaniki, M. A.; Landegren, U.; Siniossoglou, S.; Lygerou, Z.; Simos, G.; Mylonis, I. (2015)

Proliferation of cells under hypoxia is facilitated by metabolic adaptation, mediated by the transcriptional activator Hypoxia Inducible Factor-1 (HIF-1). HIF-1 alpha, the inducible subunit of HIF-1 is regulated by oxygen ...