Listar por autor "Kotoula, M. G."
Mostrando ítems 1-14 de 14
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Blood velocity pulse quantification in the human conjunctival pre-capillary arterioles
Koutsiaris, A. G.; Tachmitzi, S. V.; Papavasileiou, P.; Batis, N.; Kotoula, M. G.; Giannoukas, A. D.; Tsironi, E. (2010)Axial red blood cell velocity pulse was quantified throughout its period by high speed video microcinematography in the human eye. In 30 conjunctival precapillary arterioles (6 to 12 mu m in diameter) from 15 healthy humans, ... -
Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: A systems biology based approach
Silveira, A. C.; Morrison, M. A.; Ji, F.; Xu, H.; Reinecke, J. B.; Adams, S. M.; Arneberg, T. M.; Janssian, M.; Lee, J. E.; Yuan, Y.; Schaumberg, D. A.; Kotoula, M. G.; Tsironi, E. E.; Tsiloulis, A. N.; Chatzoulis, D. Z.; Miller, J. W.; Kim, I. K.; Hageman, G. S.; Farrer, L. A.; Haider, N. B.; DeAngelis, M. M. (2010)To identify novel genes and pathways associated with AMD, we performed microarray gene expression and linkage analysis which implicated the candidate gene, retinoic acid receptor-related orphan receptor alpha (RORA, 15q). ... -
Detection of macular photocoagulation scars with confocal infrared reflection imaging
Kotoula, M. G.; Chatzoulis, D. Z.; Tahmitzi, S.; Evangelia, T. E. (2009)■ BACKGROUND AND OBJECTIVE: To study the diagnostic reliability (specificity and sensitivity) of confocal infrared reflection in detecting threshold argon laser photocoagulation scars in the macula. ■ PATIENTS AND METHODS: ... -
Evaluation of MMP1 and MMP3 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma
Tsironi, E. E.; Pefkianaki, M.; Tsezou, A.; Kotoula, M. G.; Dardiotis, E.; Almpanidou, P.; Papathanasiou, A. A.; Rodopoulou, P.; Chatzoulis, D. Z.; Hadjigeorgiou, G. M. (2009)Purpose: To investigate possible genetic associations of matrix metalloproteinase-1 (MMP1) and MMP3 gene polymorphisms with exfoliation syndrome (XFS) with (XFS/+G) and without (XFS/-G) glaucoma in a cohort of Greek patients. ... -
Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology
Jun, G.; Nicolaou, M.; Morrison, M. A.; Buros, J.; Morgan, D. J.; Radeke, M. J.; Yonekawa, Y.; Tsironi, E. E.; Kotoula, M. G.; Zacharaki, F.; Mollema, N.; Yuan, Y.; Miller, J. W.; Haider, N. B.; Hageman, G. S.; Kim, I. K.; Schaumberg, D. A.; Farrer, L. A.; DeAngelis, M. M. (2011)ROBO1 is a strong candidate gene for age-related macular degeneration (AMD) based upon its location under a linkage peak on chromosome 3p12, its expression pattern, and its purported function in a pathway that includes ... -
Intravitreal bevacizumab for photodynamic therapy-induced massive macular detachment in acute central serous chorioretinopathy
Kotoula, M. G.; Zacharaki, F.; Tsironi, E. E. (2012)We present a long followed up case of acute central serous chorioretinopathy (CSC) complicated by a severe visual loss due to massive pigment epithelium detachment of the macula after a full-dose photodynamic therapy (PDT). ... -
Metabolic control of diabetes is associated with an improved response of diabetic retinopathy to panretinal photocoagulation
Kotoula, M. G.; Koukoulis, G. N.; Zintzaras, E.; Karabatsas, C. H.; Chatzoulis, D. Z. (2005)OBJECTIVE - To study the influence of glycemic control and the presence of microalbuminutia on the initial response to partretinal photocoagulation (PRP) in patients with a high-risk proliferative diabetic retinopathy ... -
Neovascular glaucoma as a first clinical manifestation of multiple sclerosis
Kotoula, M. G.; Katsanos, A.; Dardiotis, E.; Hadjigeorgiou, G. M.; Papadamou, G.; Chatzoulis, D. Z.; Tsironi, E. (2010)Purpose: To report a case with neovascular glaucoma caused by severe occlusive retinal vasculitis, as a first clinical manifestation of multiple sclerosis (MS). Methods: Examination on an otherwise healthy 45-year-old man ... -
Ocular disorders as the prevailing manifestations of antiphospholipid syndrome: A case series
Tsironi, E.; Gatselis, N.; Kotoula, M. G.; Zachou, K.; Pefkianaki, M.; Zacharaki, F.; Chatzoulis, D. Z.; Dalekos, G. N. (2009)Introduction: Antiphospholipid syndrome is an autoimmune disorder characterized by either a history of vascular thrombosis (one or more clinical episodes of arterial, venous, or small vessel thrombosis in any tissue or ... -
Resolution of Macular Edema in Idiopathic Juxtafoveal Telangiectasis Using PDT
Kotoula, M. G.; Chatzoulis, D. Z.; Karabatsas, C. H.; Tsiloulis, A.; Tsironi, E. E. (2009)A 57-year-old woman was treated by, photodynamic therapy for macular edema due to idiopathic juxtafoveal telangiectasis (presumed type 1A) without subretinal neovascularization. Initial visual acuity of the treated eye was ... -
A slit lamp based imaging system for measuring blood velocity in the conjunctival microcirculation of the human eye
Koutsiaris, A. G.; Tachmitzi, S. V.; Kotoula, M. G.; Karabatsas, C. H.; Tsironi, E.; Batis, N.; Chatzoulis, D. Z. (2006) -
Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration
Morrison, M. A.; Silveira, A. C.; Huynh, N.; Jun, G.; Smith, S. E.; Zacharaki, F.; Sato, H.; Loomis, S.; Andreoli, M. T.; Adams, S. M.; Radeke, M. J.; Jelcick, A. S.; Yuan, Y.; Tsiloulis, A. N.; Chatzoulis, D. Z.; Silvestri, G.; Kotoula, M. G.; Tsironi, E. E.; Hollis, B. W.; Chen, R.; Haider, N. B.; Miller, J. W.; Farrer, L. A.; Hageman, G. S.; Kim, I. K.; Schaumberg, D. A.; DeAngelis, M. M. (2011)Vitamin D has been shown to have anti-angiogenic properties and to play a protective role in several types of cancer, including breast, prostate and cutaneous melanoma. Similarly, vitamin D levels have been shown to be ... -
Unexplained choroidal embolisation: remember the antiphospholipid syndrome
Tsironi, E.; Gatselis, N.; Kotoula, M. G.; Chatzoulis, D. Z.; Dalekos, G. N. (2006) -
Volume flow and wall shear stress quantification in the human conjunctival capillaries and post-capillary venules in vivo
Koutsiaris, A. G.; Tachmitzi, S. V.; Batis, N.; Kotoula, M. G.; Karabatsas, C. H.; Tsironi, E.; Chatzoulis, D. Z. (2007)Understanding the mathematical relationships of volume blood flow and wall shear stress with respect to microvessel diameter is necessary for the study of vascular design. Here, for the first time, volume flow and wall ...